node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP12B | FIBCD1 | ENSBTAP00000004395 | ENSBTAP00000023924 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Fibrinogen C domain containing 1. | 0.406 |
AQP12B | JMJD4 | ENSBTAP00000004395 | ENSBTAP00000005487 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Jumonji domain containing 4. | 0.481 |
AQP12B | TMEM187 | ENSBTAP00000004395 | ENSBTAP00000010891 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Transmembrane protein 187. | 0.566 |
FIBCD1 | AQP12B | ENSBTAP00000023924 | ENSBTAP00000004395 | Fibrinogen C domain containing 1. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.406 |
FIBCD1 | JMJD4 | ENSBTAP00000023924 | ENSBTAP00000005487 | Fibrinogen C domain containing 1. | Jumonji domain containing 4. | 0.569 |
FIBCD1 | TMEM187 | ENSBTAP00000023924 | ENSBTAP00000010891 | Fibrinogen C domain containing 1. | Transmembrane protein 187. | 0.575 |
GNL3L | TMEM187 | ENSBTAP00000072870 | ENSBTAP00000010891 | Guanine nucleotide-binding protein-like 3-like protein; Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal proces [...] | Transmembrane protein 187. | 0.697 |
JMJD4 | AQP12B | ENSBTAP00000005487 | ENSBTAP00000004395 | Jumonji domain containing 4. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.481 |
JMJD4 | FIBCD1 | ENSBTAP00000005487 | ENSBTAP00000023924 | Jumonji domain containing 4. | Fibrinogen C domain containing 1. | 0.569 |
JMJD4 | TMEM187 | ENSBTAP00000005487 | ENSBTAP00000010891 | Jumonji domain containing 4. | Transmembrane protein 187. | 0.660 |
LAGE3 | OSGEP | ENSBTAP00000069256 | ENSBTAP00000003557 | L antigen family member 3. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.997 |
LAGE3 | OSGEPL1 | ENSBTAP00000069256 | ENSBTAP00000016671 | L antigen family member 3. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.946 |
LAGE3 | TMEM187 | ENSBTAP00000069256 | ENSBTAP00000010891 | L antigen family member 3. | Transmembrane protein 187. | 0.753 |
LAGE3 | TP53RK | ENSBTAP00000069256 | ENSBTAP00000038979 | L antigen family member 3. | TP53 regulating kinase. | 0.936 |
OSGEP | LAGE3 | ENSBTAP00000003557 | ENSBTAP00000069256 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | L antigen family member 3. | 0.997 |
OSGEP | OSGEPL1 | ENSBTAP00000003557 | ENSBTAP00000016671 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.547 |
OSGEP | TMEM187 | ENSBTAP00000003557 | ENSBTAP00000010891 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Transmembrane protein 187. | 0.651 |
OSGEP | TP53RK | ENSBTAP00000003557 | ENSBTAP00000038979 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | TP53 regulating kinase. | 0.994 |
OSGEPL1 | LAGE3 | ENSBTAP00000016671 | ENSBTAP00000069256 | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | L antigen family member 3. | 0.946 |
OSGEPL1 | OSGEP | ENSBTAP00000016671 | ENSBTAP00000003557 | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.547 |