STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FLI1Friend leukemia integration 1 transcription factor; Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3' (By similarity) (451 aa)    
Predicted Functional Partners:
ENSBTAG00000045692
Uncharacterized protein
   
  
 0.830
CDH5
Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recrui [...]
   
  
 0.829
GATA1
GATA binding protein 1 (globin transcription factor 1)
   
 
 0.719
ENSBTAG00000030470
Uncharacterized protein
    
 
 0.708
ZNF160
Uncharacterized protein
    
 
 0.704
ZNF43
Uncharacterized protein
    
 
 0.679
ZNF35
Zinc finger protein 35
    
 
 0.647
RUNX1
Runt-related transcription factor; CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters
   
 
 0.641
ZSCAN21
Bos taurus zinc finger and SCAN domain containing 21 (ZSCAN21), mRNA
    
 
 0.630
LMO2
Rhombotin-2; Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state
   
 
 0.625
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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