STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PON2Serum paraoxonase/arylesterase 2; Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters; Belongs to the paraoxonase family. (354 aa)    
Predicted Functional Partners:
PON3
Paraoxonase 3.
  
0.732
ARSK
Arylsulfatase K.
   
 
 0.637
CHST10
Carbohydrate sulfotransferase.
    
 
 0.598
CHST12
Carbohydrate sulfotransferase.
    
 
 0.572
CLSPN
Claspin.
      
 0.531
GML
Glycosylphosphatidylinositol anchored molecule like protein.
      
 0.530
PARK7
Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...]
      
 0.528
CNPY4
Protein canopy homolog 4; Plays a role in the regulation of the cell surface expression of TLR4.
      
 0.522
PON1
Paraoxonase 1.
  
  
 
0.507
LRRC40
Leucine rich repeat containing 40.
    
 
 0.486
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.