node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUD31 | CDC40 | ENSBTAP00000061709 | ENSBTAP00000059117 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Cell division cycle 40. | 0.983 |
BUD31 | CDC5L | ENSBTAP00000061709 | ENSBTAP00000026654 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | 0.993 |
BUD31 | CRNKL1 | ENSBTAP00000061709 | ENSBTAP00000011148 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Crooked neck pre-mRNA splicing factor 1. | 0.996 |
BUD31 | CWC22 | ENSBTAP00000061709 | ENSBTAP00000062978 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | CWC22 spliceosome associated protein homolog. | 0.992 |
BUD31 | DHX38 | ENSBTAP00000061709 | ENSBTAP00000042866 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; Probable ATP-binding RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. | 0.981 |
BUD31 | PRPF18 | ENSBTAP00000061709 | ENSBTAP00000061262 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. | 0.970 |
BUD31 | PRPF19 | ENSBTAP00000061709 | ENSBTAP00000019100 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 comp [...] | 0.991 |
BUD31 | PRPF8 | ENSBTAP00000061709 | ENSBTAP00000043577 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pre-mRNA processing factor 8. | 0.987 |
BUD31 | SLU7 | ENSBTAP00000061709 | ENSBTAP00000011131 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. | 0.977 |
BUD31 | SYF2 | ENSBTAP00000061709 | ENSBTAP00000002165 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | SYF2 pre-mRNA splicing factor. | 0.985 |
CDC40 | BUD31 | ENSBTAP00000059117 | ENSBTAP00000061709 | Cell division cycle 40. | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity; Belongs to the BUD31 (G10) family. | 0.983 |
CDC40 | CDC5L | ENSBTAP00000059117 | ENSBTAP00000026654 | Cell division cycle 40. | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | 0.992 |
CDC40 | CRNKL1 | ENSBTAP00000059117 | ENSBTAP00000011148 | Cell division cycle 40. | Crooked neck pre-mRNA splicing factor 1. | 0.985 |
CDC40 | CWC22 | ENSBTAP00000059117 | ENSBTAP00000062978 | Cell division cycle 40. | CWC22 spliceosome associated protein homolog. | 0.997 |
CDC40 | DHX38 | ENSBTAP00000059117 | ENSBTAP00000042866 | Cell division cycle 40. | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; Probable ATP-binding RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. | 0.997 |
CDC40 | PRPF18 | ENSBTAP00000059117 | ENSBTAP00000061262 | Cell division cycle 40. | Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. | 0.905 |
CDC40 | PRPF19 | ENSBTAP00000059117 | ENSBTAP00000019100 | Cell division cycle 40. | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 comp [...] | 0.980 |
CDC40 | PRPF8 | ENSBTAP00000059117 | ENSBTAP00000043577 | Cell division cycle 40. | Pre-mRNA processing factor 8. | 0.983 |
CDC40 | SLU7 | ENSBTAP00000059117 | ENSBTAP00000011131 | Cell division cycle 40. | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. | 0.995 |
CDC40 | SYF2 | ENSBTAP00000059117 | ENSBTAP00000002165 | Cell division cycle 40. | SYF2 pre-mRNA splicing factor. | 0.997 |