STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHD1Pleckstrin homology and coiled-coil domain containing D1. (506 aa)    
Predicted Functional Partners:
SLC10A1
Solute carrier family 10 (Sodium/bile acid cotransporter family), member 1.
      
 0.603
C8B
Complement C8 beta chain.
      
 0.576
SLC39A9
Solute carrier family 39 member 9.
 
    
 0.570
TOPAZ1
Protein TOPAZ1; Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
      
 0.509
MLANA
Melan-A.
      
 0.487
ARHGAP30
Rho GTPase activating protein 30.
      
 0.481
TMEM92
Uncharacterized protein.
      
 0.480
KLHDC10
Kelch domain-containing protein 10; Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5 (By similarity).
   
  
 0.475
SLC39A6
Solute carrier family 39 member 6.
      
 0.439
RNF165
Ring finger protein 165.
      
 0.436
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.