STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (279 aa)    
Predicted Functional Partners:
C28H1orf198
Uncharacterized protein C1orf198 homolog.
      
 0.701
FCRL6
Fc receptor like 6.
      
 0.565
ABTB2
Ankyrin repeat and BTB domain containing 2.
      
 0.563
DHRS9
Dehydrogenase/reductase SDR family member 9; 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha- tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Plays also a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH.
      
 0.548
NEDD9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 
 0.528
SAP30BP
SAP30 binding protein.
      
 0.525
NDFIP2
Nedd4 family interacting protein 2.
    
 
 0.444
PRSS22
Serine protease 22; Belongs to the peptidase S1 family.
      
 0.438
RBM6
RNA binding motif protein 6.
      
 0.437
RBM24
RNA binding motif protein 24.
      
 0.435
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: low (30%) [HD]