node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABAT | ACSS2 | ENSBTAP00000005280 | ENSBTAP00000067480 | 4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acyl-CoA synthetase short chain family member 2. | 0.829 |
ABAT | ALDH2 | ENSBTAP00000005280 | ENSBTAP00000011521 | 4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | 0.947 |
ABAT | ALDH6A1 | ENSBTAP00000005280 | ENSBTAP00000058160 | 4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. | 0.960 |
ABAT | EHHADH | ENSBTAP00000005280 | ENSBTAP00000053200 | 4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. | 0.936 |
ACSS2 | ABAT | ENSBTAP00000067480 | ENSBTAP00000005280 | Acyl-CoA synthetase short chain family member 2. | 4-aminobutyrate aminotransferase, mitochondrial; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.829 |
ACSS2 | ALDH2 | ENSBTAP00000067480 | ENSBTAP00000011521 | Acyl-CoA synthetase short chain family member 2. | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | 0.946 |
ACSS2 | ALDH6A1 | ENSBTAP00000067480 | ENSBTAP00000058160 | Acyl-CoA synthetase short chain family member 2. | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. | 0.917 |
ACSS2 | EHHADH | ENSBTAP00000067480 | ENSBTAP00000053200 | Acyl-CoA synthetase short chain family member 2. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. | 0.885 |
ADH4 | ADH5 | ENSBTAP00000003769 | ENSBTAP00000021304 | PKS_ER domain-containing protein. | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.903 |
ADH4 | ADH6 | ENSBTAP00000003769 | ENSBTAP00000009191 | PKS_ER domain-containing protein. | Uncharacterized protein. | 0.911 |
ADH4 | ALDH2 | ENSBTAP00000003769 | ENSBTAP00000011521 | PKS_ER domain-containing protein. | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | 0.967 |
ADH4 | MAOA | ENSBTAP00000003769 | ENSBTAP00000021570 | PKS_ER domain-containing protein. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. | 0.913 |
ADH4 | MAOB | ENSBTAP00000003769 | ENSBTAP00000001698 | PKS_ER domain-containing protein. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity); Belongs to the flavin monoamine oxidase family. | 0.913 |
ADH5 | ADH4 | ENSBTAP00000021304 | ENSBTAP00000003769 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | PKS_ER domain-containing protein. | 0.903 |
ADH5 | ADH6 | ENSBTAP00000021304 | ENSBTAP00000009191 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Uncharacterized protein. | 0.902 |
ADH5 | ALDH2 | ENSBTAP00000021304 | ENSBTAP00000011521 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | 0.969 |
ADH5 | MAOA | ENSBTAP00000021304 | ENSBTAP00000021570 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. | 0.920 |
ADH5 | MAOB | ENSBTAP00000021304 | ENSBTAP00000001698 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity); Belongs to the flavin monoamine oxidase family. | 0.931 |
ADH6 | ADH4 | ENSBTAP00000009191 | ENSBTAP00000003769 | Uncharacterized protein. | PKS_ER domain-containing protein. | 0.911 |
ADH6 | ADH5 | ENSBTAP00000009191 | ENSBTAP00000021304 | Uncharacterized protein. | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.902 |