node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | BPGM | ENSBTAP00000057869 | ENSBTAP00000011713 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | 0.933 |
ALDOA | ENO1 | ENSBTAP00000057869 | ENSBTAP00000017839 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.979 |
ALDOA | ENO2 | ENSBTAP00000057869 | ENSBTAP00000014978 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | ENO2 protein. | 0.962 |
ALDOA | ENO3 | ENSBTAP00000057869 | ENSBTAP00000063298 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | 0.976 |
ALDOA | ENO4 | ENSBTAP00000057869 | ENSBTAP00000043066 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Enolase 4. | 0.946 |
ALDOA | GAPDH | ENSBTAP00000057869 | ENSBTAP00000062798 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.993 |
ALDOA | GAPDHS | ENSBTAP00000057869 | ENSBTAP00000021166 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.978 |
ALDOA | MINPP1 | ENSBTAP00000057869 | ENSBTAP00000007784 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. | 0.800 |
ALDOA | PGAM2 | ENSBTAP00000057869 | ENSBTAP00000019336 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate mutase 2; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.942 |
ALDOA | PGK1 | ENSBTAP00000057869 | ENSBTAP00000001187 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.929 |
BPGM | ALDOA | ENSBTAP00000011713 | ENSBTAP00000057869 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.933 |
BPGM | ENO1 | ENSBTAP00000011713 | ENSBTAP00000017839 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.978 |
BPGM | ENO2 | ENSBTAP00000011713 | ENSBTAP00000014978 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | ENO2 protein. | 0.974 |
BPGM | ENO3 | ENSBTAP00000011713 | ENSBTAP00000063298 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | 0.981 |
BPGM | ENO4 | ENSBTAP00000011713 | ENSBTAP00000043066 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Enolase 4. | 0.953 |
BPGM | GAPDH | ENSBTAP00000011713 | ENSBTAP00000062798 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.961 |
BPGM | GAPDHS | ENSBTAP00000011713 | ENSBTAP00000021166 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.953 |
BPGM | MINPP1 | ENSBTAP00000011713 | ENSBTAP00000007784 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. | 0.938 |
BPGM | PGAM2 | ENSBTAP00000011713 | ENSBTAP00000019336 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Phosphoglycerate mutase 2; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.933 |
BPGM | PGK1 | ENSBTAP00000011713 | ENSBTAP00000001187 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.988 |