STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM98Transmembrane protein 98; Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1). (226 aa)    
Predicted Functional Partners:
PRSS56
Serine protease 56; Belongs to the peptidase S1 family.
      
 0.875
TMEM176A
Transmembrane protein 176A.
      
 0.692
TMEM229B
Transmembrane protein 229B.
      
 0.662
TSPAN11
Tetraspanin-11.
      
 0.657
MYRF
Myelin regulatory factor.
      
 0.626
PPP1R32
Protein phosphatase 1 regulatory subunit 32.
      
 0.608
TAFA2
TAFA chemokine like family member 2.
      
 0.603
KANSL3
KAT8 regulatory NSL complex subunit 3.
      
 0.597
TMEM9B
TMEM9 domain family, member B.
   
  
 0.587
KIAA1211
KIAA1211.
      
 0.587
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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