STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLIS2Bos taurus GLIS family zinc finger 2 (GLIS2), mRNA (524 aa)    
Predicted Functional Partners:
CBFA2T3
CBFA2/RUNX1 translocation partner 3; Core-binding factor, runt domain, alpha subunit 2; translocated to, 3
   
 
 0.677
INVS
Inversin; Bos taurus inversin (INVS), mRNA
    
 
 0.672
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
    
 
 0.655
ADCY9
Adenylyl CYclase family member (Acy-1)-like; Bos taurus adenylate cyclase 9 (ADCY9), mRNA; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family
   
 
 0.637
ARMC8
Bos taurus armadillo repeat containing 8 (ARMC8), mRNA
      
 0.628
FGF18
Fibroblast growth factor 18; Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation (By similarity)
    
 
 0.591
NEK8
Uncharacterized protein; Bos taurus NIMA (never in mitosis gene a)- related kinase 8 (NEK8), mRNA
    
 
 0.591
TMEM37
Bos taurus transmembrane protein 37 (TMEM37), mRNA
      
 0.581
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide t [...]
    
 
 0.576
TTC21B
Bos taurus tetratricopeptide repeat domain 21B (TTC21B), mRNA
      
 0.570
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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