STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM131BProtein FAM131B; Bos taurus family with sequence similarity 131, member B (FAM131B), mRNA; Belongs to the FAM131 family (339 aa)    
Predicted Functional Partners:
KIAA1549
KIAA1549
   
  
 0.816
RNF130
Bos taurus ring finger protein 130 (RNF130), mRNA
   
  
 0.729
CLCN6
Chloride channel, voltage-sensitive 6
   
  
 0.714
MKRN1
Bos taurus makorin ring finger protein 1 (MKRN1), mRNA
      
 0.699
GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]
   
  
 0.681
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
   
  
 0.679
NCOA2
Nuclear receptor coactivator 2
    
 
 0.584
SRGAP2
Uncharacterized protein; Bos taurus SLIT-ROBO Rho GTPase activating protein 2 (SRGAP2), mRNA
   
  
 0.540
FAM171B
Uncharacterized protein; Bos taurus family with sequence similarity 171, member B (FAM171B), mRNA
   
  
 0.533
TMEM130
Transmembrane protein 130
   
  
 0.533
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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