STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAGAAlpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to the glycosyl hydrolase 27 family (411 aa)    
Predicted Functional Partners:
HEXA
Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues
  
 
 0.947
B3GALNT1
Hexosyltransferase; beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
     
 0.941
HEXB
Beta-hexosaminidase; Bos taurus hexosaminidase B (beta polypeptide) (HEXB), mRNA
  
 
 0.936
B3GALT5
Hexosyltransferase; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
     
 0.902
CCNJ
Cyclin J; Belongs to the cyclin family
      
 0.817
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3)
   
  
 0.812
MAN2B2
Alpha-mannosidase
   
 
 0.744
HEXDC
Hexosaminidase D; Has hexosaminidase activity
      
 0.712
GLB1
Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans
  
  
 0.708
CCDC136
Coiled-coil domain containing 136
      
 0.678
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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