STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGL2Fibroleukin; May play a role in physiologic lymphocyte functions at mucosal sites. (441 aa)    
Predicted Functional Partners:
CTLA4
Cytotoxic T-lymphocyte-associated protein 4.
      
 0.548
FCGR3A
Low affinity immunoglobulin gamma Fc region receptor III; Is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Also mediates antibody-dependent cellular toxicity (By similarity).
   
  
 0.548
CST7
Cystatin F.
      
 0.540
LAG3
Lymphocyte activating 3.
    
 
 0.528
MATN2
MATN2 protein.
   
 
 0.527
VSIR
V-set immunoregulatory receptor.
   
  
 0.514
KLRG1
Killer cell lectin like receptor G1.
   
 
 0.505
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.
   
 
 0.487
SLC4A7
Anion exchange protein.
      
 0.478
BHMT2
Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.
   
  
 0.465
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.