STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPSA40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (315 aa)    
Predicted Functional Partners:
RPS2
40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
  
 0.999
RPS11
40S ribosomal protein S11.
  
 0.999
RPS5
40S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family.
  
 0.999
RPLP0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
  
 
 0.999
RPS16-2
40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.
  
 0.999
RPS18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; Belongs to the universal ribosomal protein uS13 family.
  
 0.999
RPL18
60S ribosomal protein L18.
  
 
 0.999
RPL23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.998
RPS29-2
40S ribosomal protein S29.
  
 0.998
RPL24
60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family.
  
 
 0.998
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.