STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTF2IRD2General transcription factor II-I repeat domain-containing protein 2. (950 aa)    
Predicted Functional Partners:
LGI3
Leucine rich repeat LGI family member 3.
    
 
 0.582
SEC14L5
SEC14 like lipid binding 5.
    
 
 0.580
GCFC2
GC-rich sequence DNA-binding factor 2.
      
 0.568
SERF1A
Small EDRK-rich factor 1; Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity). Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates (By similarity).
      
 0.567
ZNF449-2
Zinc finger protein 449.
      
 0.565
ZNF449
Uncharacterized protein.
      
 0.564
NME6
Nucleoside diphosphate kinase.
    
 0.535
RHBDD2
Rhomboid domain containing 2.
      
 0.483
PRRC2B
Proline rich coiled-coil 2B.
      
 0.481
SLC45A1
Solute carrier family 45 member 1.
      
 0.480
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.