node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGMAT | ARG1 | ENSBTAP00000067134 | ENSBTAP00000016461 | Agmatinase; Belongs to the arginase family. | Arginase-1. | 0.490 |
AGMAT | ARG2 | ENSBTAP00000067134 | ENSBTAP00000053934 | Agmatinase; Belongs to the arginase family. | Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signal [...] | 0.526 |
AGMAT | CBS | ENSBTAP00000067134 | ENSBTAP00000063539 | Agmatinase; Belongs to the arginase family. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.482 |
AGMAT | CRYM | ENSBTAP00000067134 | ENSBTAP00000012972 | Agmatinase; Belongs to the arginase family. | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | 0.786 |
ARG1 | AGMAT | ENSBTAP00000016461 | ENSBTAP00000067134 | Arginase-1. | Agmatinase; Belongs to the arginase family. | 0.490 |
ARG1 | ARG2 | ENSBTAP00000016461 | ENSBTAP00000053934 | Arginase-1. | Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signal [...] | 0.911 |
ARG1 | CBS | ENSBTAP00000016461 | ENSBTAP00000063539 | Arginase-1. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.421 |
ARG1 | CRYM | ENSBTAP00000016461 | ENSBTAP00000012972 | Arginase-1. | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | 0.786 |
ARG2 | AGMAT | ENSBTAP00000053934 | ENSBTAP00000067134 | Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signal [...] | Agmatinase; Belongs to the arginase family. | 0.526 |
ARG2 | ARG1 | ENSBTAP00000053934 | ENSBTAP00000016461 | Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signal [...] | Arginase-1. | 0.911 |
ARG2 | CRYM | ENSBTAP00000053934 | ENSBTAP00000012972 | Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signal [...] | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | 0.791 |
CBS | AGMAT | ENSBTAP00000063539 | ENSBTAP00000067134 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Agmatinase; Belongs to the arginase family. | 0.482 |
CBS | ARG1 | ENSBTAP00000063539 | ENSBTAP00000016461 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Arginase-1. | 0.421 |
CBS | CRYM | ENSBTAP00000063539 | ENSBTAP00000012972 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | 0.673 |
CRAMP1 | CRYM | ENSBTAP00000002854 | ENSBTAP00000012972 | Uncharacterized protein. | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | 0.640 |
CRAMP1 | THAP7 | ENSBTAP00000002854 | ENSBTAP00000053395 | Uncharacterized protein. | THAP domain containing 7. | 0.725 |
CRYM | AGMAT | ENSBTAP00000012972 | ENSBTAP00000067134 | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | Agmatinase; Belongs to the arginase family. | 0.786 |
CRYM | ARG1 | ENSBTAP00000012972 | ENSBTAP00000016461 | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | Arginase-1. | 0.786 |
CRYM | ARG2 | ENSBTAP00000012972 | ENSBTAP00000053934 | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | Arginase-2, mitochondrial; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signal [...] | 0.791 |
CRYM | CBS | ENSBTAP00000012972 | ENSBTAP00000063539 | Ketimine reductase mu-crystallin; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.673 |