node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP1A1 | CYP1A2 | ENSBTAP00000053212 | ENSBTAP00000000094 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.939 |
CYP1A1 | CYP1B1 | ENSBTAP00000053212 | ENSBTAP00000057658 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.932 |
CYP1A1 | CYP2E1 | ENSBTAP00000053212 | ENSBTAP00000024437 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | 0.940 |
CYP1A1 | EPHX1 | ENSBTAP00000053212 | ENSBTAP00000070698 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.984 |
CYP1A1 | MGST1 | ENSBTAP00000053212 | ENSBTAP00000011257 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity (By similarity); Belongs to the MAPEG family. | 0.922 |
CYP1A1 | MGST3 | ENSBTAP00000053212 | ENSBTAP00000013559 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Microsomal glutathione S-transferase 3; Also functions as a glutathione peroxidase. | 0.912 |
CYP1A2 | CYP1A1 | ENSBTAP00000000094 | ENSBTAP00000053212 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.939 |
CYP1A2 | CYP1B1 | ENSBTAP00000000094 | ENSBTAP00000057658 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.942 |
CYP1A2 | CYP2E1 | ENSBTAP00000000094 | ENSBTAP00000024437 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | 0.945 |
CYP1A2 | EPHX1 | ENSBTAP00000000094 | ENSBTAP00000070698 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.964 |
CYP1A2 | MGST1 | ENSBTAP00000000094 | ENSBTAP00000011257 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity (By similarity); Belongs to the MAPEG family. | 0.913 |
CYP1A2 | MGST3 | ENSBTAP00000000094 | ENSBTAP00000013559 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | Microsomal glutathione S-transferase 3; Also functions as a glutathione peroxidase. | 0.906 |
CYP1B1 | CYP1A1 | ENSBTAP00000057658 | ENSBTAP00000053212 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.932 |
CYP1B1 | CYP1A2 | ENSBTAP00000057658 | ENSBTAP00000000094 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.942 |
CYP1B1 | EPHX1 | ENSBTAP00000057658 | ENSBTAP00000070698 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.970 |
CYP1B1 | MGST1 | ENSBTAP00000057658 | ENSBTAP00000011257 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity (By similarity); Belongs to the MAPEG family. | 0.917 |
CYP1B1 | MGST3 | ENSBTAP00000057658 | ENSBTAP00000013559 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Microsomal glutathione S-transferase 3; Also functions as a glutathione peroxidase. | 0.915 |
CYP2E1 | CYP1A1 | ENSBTAP00000024437 | ENSBTAP00000053212 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.940 |
CYP2E1 | CYP1A2 | ENSBTAP00000024437 | ENSBTAP00000000094 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.945 |
CYP2E1 | EPHX1 | ENSBTAP00000024437 | ENSBTAP00000070698 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.960 |