ENAM protein (Bos taurus) - STRING interaction network

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Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBN	AMELX	ENSBTAP00000052338	ENSBTAP00000016034	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	0.924
AMBN	AMTN	ENSBTAP00000052338	ENSBTAP00000003804	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Amelotin.	0.941
AMBN	DMP1	ENSBTAP00000052338	ENSBTAP00000025468	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Dentin matrix acidic phosphoprotein 1; May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast- specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite (By similarity).	0.608
AMBN	ENAM	ENSBTAP00000052338	ENSBTAP00000013661	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Enamelin.	0.960
AMBN	FAM20A	ENSBTAP00000052338	ENSBTAP00000001439	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	FAM20A golgi associated secretory pathway pseudokinase.	0.773
AMBN	FAM83H	ENSBTAP00000052338	ENSBTAP00000068570	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Family with sequence similarity 83 member H.	0.652
AMBN	KLK4	ENSBTAP00000052338	ENSBTAP00000027207	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Kallikrein related peptidase 4; Belongs to the peptidase S1 family.	0.908
AMBN	MMP20	ENSBTAP00000052338	ENSBTAP00000018936	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Matrix metalloproteinase-20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Ser-\|-Phe-361' site.	0.861
AMBN	ODAM	ENSBTAP00000052338	ENSBTAP00000039362	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.	0.796
AMBN	TUFT1	ENSBTAP00000052338	ENSBTAP00000043710	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	Tuftelin; Involved in the mineralization and structural organization of enamel.	0.871
AMELX	AMBN	ENSBTAP00000016034	ENSBTAP00000052338	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Ameloblastin; Involved in the mineralization and structural organization of enamel; Belongs to the ameloblastin family.	0.924
AMELX	AMTN	ENSBTAP00000016034	ENSBTAP00000003804	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Amelotin.	0.840
AMELX	DMP1	ENSBTAP00000016034	ENSBTAP00000025468	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Dentin matrix acidic phosphoprotein 1; May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast- specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite (By similarity).	0.698
AMELX	ENAM	ENSBTAP00000016034	ENSBTAP00000013661	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Enamelin.	0.903
AMELX	FAM20A	ENSBTAP00000016034	ENSBTAP00000001439	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	FAM20A golgi associated secretory pathway pseudokinase.	0.724
AMELX	FAM83H	ENSBTAP00000016034	ENSBTAP00000068570	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Family with sequence similarity 83 member H.	0.701
AMELX	KLK4	ENSBTAP00000016034	ENSBTAP00000027207	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Kallikrein related peptidase 4; Belongs to the peptidase S1 family.	0.873
AMELX	MMP20	ENSBTAP00000016034	ENSBTAP00000018936	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Matrix metalloproteinase-20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Ser-\|-Phe-361' site.	0.881
AMELX	ODAM	ENSBTAP00000016034	ENSBTAP00000039362	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.	0.780
AMELX	TUFT1	ENSBTAP00000016034	ENSBTAP00000043710	Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.	Tuftelin; Involved in the mineralization and structural organization of enamel.	0.746

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