STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP23Matrix metalloproteinase-23, soluble form; Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity); Belongs to the peptidase M10A family. (420 aa)    
Predicted Functional Partners:
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
      
 0.597
COL6A2
Collagen type VI alpha 2 chain.
   
 
 0.545
COL16A1
Collagen type XVI alpha 1 chain.
   
 
 0.523
TIMP2
Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.
   
 
 0.515
ATOH8
Atonal bHLH transcription factor 8.
      
 0.491
LAYN
Layilin.
    
 
 0.488
CAB39
Calcium-binding protein 39; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity).
      
 0.484
BCL6B
BCL6B transcription repressor.
      
 0.482
OR6C1
Olfactory receptor.
      
 0.480
THSD1
Thrombospondin type-1 domain-containing protein 1.
   
  
 0.477
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.