STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RESP18Regulated endocrine-specific protein 18; May play an important regulatory role in corticotrophs. Belongs to the RESP18 family. (174 aa)    
Predicted Functional Partners:
FLYWCH2
FLYWCH family member 2.
      
 0.623
PCSK2
Neuroendocrine convertase 2; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells (By similarity).
   
  
 0.603
IQSEC3
IQ motif and Sec7 domain 3.
   
  
 0.599
OR5A1
Olfactory receptor.
      
 0.576
IGLON5
IgLON family member 5.
   
 
 0.496
TANC1
Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1.
    
 
 0.496
RASAL3
RAS protein activator like-3; Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down- stream ERK signaling pathway.
    
 
 0.492
IGSF21
Immunoglobin superfamily member 21.
   
 
 0.490
TUBGCP6
Tubulin gamma complex associated protein 6.
      
 0.482
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
      
 0.481
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.