node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
H2AC18 | H2B | ENSBTAP00000042479 | ENSBTAP00000047687 | Histone H2A; Belongs to the histone H2A family. | Histone H2B type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.712 |
H2AC18 | H2B-3 | ENSBTAP00000042479 | ENSBTAP00000049501 | Histone H2A; Belongs to the histone H2A family. | Histone H2B; Belongs to the histone H2B family. | 0.630 |
H2AC18 | HDAC10 | ENSBTAP00000042479 | ENSBTAP00000014602 | Histone H2A; Belongs to the histone H2A family. | Histone deacetylase 10. | 0.744 |
H2AC18 | HDAC8 | ENSBTAP00000042479 | ENSBTAP00000072222 | Histone H2A; Belongs to the histone H2A family. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility (By similarity). | 0.701 |
H2AC18 | HIST1H3C | ENSBTAP00000042479 | ENSBTAP00000059273 | Histone H2A; Belongs to the histone H2A family. | Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.619 |
H2AC18 | LOC788077 | ENSBTAP00000042479 | ENSBTAP00000062977 | Histone H2A; Belongs to the histone H2A family. | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.619 |
H2AC18 | NCOR2 | ENSBTAP00000042479 | ENSBTAP00000060821 | Histone H2A; Belongs to the histone H2A family. | Nuclear receptor corepressor 2. | 0.402 |
H2AC18 | SIRT1 | ENSBTAP00000042479 | ENSBTAP00000018630 | Histone H2A; Belongs to the histone H2A family. | Sirtuin 1. | 0.552 |
H2AFY | H2B | ENSBTAP00000021436 | ENSBTAP00000047687 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H2B type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.564 |
H2AFY | H2B-3 | ENSBTAP00000021436 | ENSBTAP00000049501 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H2B; Belongs to the histone H2B family. | 0.524 |
H2AFY | HDAC10 | ENSBTAP00000021436 | ENSBTAP00000014602 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone deacetylase 10. | 0.737 |
H2AFY | HDAC8 | ENSBTAP00000021436 | ENSBTAP00000072222 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility (By similarity). | 0.750 |
H2AFY | HIST1H3C | ENSBTAP00000021436 | ENSBTAP00000059273 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.578 |
H2AFY | LOC788077 | ENSBTAP00000021436 | ENSBTAP00000062977 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.579 |
H2AFY2 | H2B | ENSBTAP00000001547 | ENSBTAP00000047687 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H2B type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.572 |
H2AFY2 | H2B-3 | ENSBTAP00000001547 | ENSBTAP00000049501 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H2B; Belongs to the histone H2B family. | 0.572 |
H2AFY2 | HDAC10 | ENSBTAP00000001547 | ENSBTAP00000014602 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone deacetylase 10. | 0.737 |
H2AFY2 | HDAC8 | ENSBTAP00000001547 | ENSBTAP00000072222 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility (By similarity). | 0.744 |
H2AFY2 | HIST1H3C | ENSBTAP00000001547 | ENSBTAP00000059273 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.491 |
H2AFY2 | LOC788077 | ENSBTAP00000001547 | ENSBTAP00000062977 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.491 |