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STRINGSTRING
BCHE protein (Bos taurus) - STRING interaction network
"BCHE" - Cholinesterase in Bos taurus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCHECholinesterase; Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters (By similarity) (602 aa)    
Predicted Functional Partners:
GHRL
Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity) (133 aa)
         
  0.926
COCH
Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork (550 aa)
           
  0.786
APP
Amyloid-beta A4 protein; Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O) (695 aa)
     
 
  0.736
COLQ
Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase (454 aa)
     
 
  0.722
ALB
Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (607 aa)
     
   
  0.712
SLC18A3
Solute carrier family 18 (vesicular acetylcholine transporter), member 3 (524 aa)
     
   
  0.677
BRCA2
BRCA2, DNA repair associated; Breast cancer 2, early onset (3357 aa)
           
  0.669
PON1
Bos taurus paraoxonase 1 (PON1), mRNA (355 aa)
     
   
  0.664
MUSK
Uncharacterized protein; Bos taurus muscle, skeletal, receptor tyrosine kinase (MUSK), mRNA (952 aa)
       
 
  0.651
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family (527 aa)
     
   
  0.629
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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