node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTN4 | PDLIM1 | ENSBTAP00000071047 | ENSBTAP00000014850 | Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcri [...] | PDZ and LIM domain protein 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity). | 0.630 |
ACTN4 | PDLIM2 | ENSBTAP00000071047 | ENSBTAP00000065726 | Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcri [...] | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity). | 0.666 |
ACTN4 | PDLIM5 | ENSBTAP00000071047 | ENSBTAP00000054445 | Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcri [...] | PDZ and LIM domain 5. | 0.616 |
DPYSL3 | EHBP1 | ENSBTAP00000014091 | ENSBTAP00000053319 | Dihydropyrimidinase like 3. | EH domain binding protein 1. | 0.553 |
DPYSL3 | EHBP1L1 | ENSBTAP00000014091 | ENSBTAP00000008891 | Dihydropyrimidinase like 3. | EH domain binding protein 1 like 1. | 0.569 |
DPYSL3 | MYO1A | ENSBTAP00000014091 | ENSBTAP00000068102 | Dihydropyrimidinase like 3. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.720 |
DPYSL3 | PDLIM1 | ENSBTAP00000014091 | ENSBTAP00000014850 | Dihydropyrimidinase like 3. | PDZ and LIM domain protein 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity). | 0.593 |
DPYSL3 | PDLIM2 | ENSBTAP00000014091 | ENSBTAP00000065726 | Dihydropyrimidinase like 3. | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity). | 0.540 |
DPYSL3 | PDLIM5 | ENSBTAP00000014091 | ENSBTAP00000054445 | Dihydropyrimidinase like 3. | PDZ and LIM domain 5. | 0.540 |
DPYSL3 | SMTNL1 | ENSBTAP00000014091 | ENSBTAP00000041378 | Dihydropyrimidinase like 3. | Smoothelin like 1. | 0.540 |
DPYSL3 | SMTNL2 | ENSBTAP00000014091 | ENSBTAP00000027457 | Dihydropyrimidinase like 3. | Smoothelin-like protein 2; Belongs to the smoothelin family. | 0.540 |
EHBP1 | DPYSL3 | ENSBTAP00000053319 | ENSBTAP00000014091 | EH domain binding protein 1. | Dihydropyrimidinase like 3. | 0.553 |
EHBP1 | EHBP1L1 | ENSBTAP00000053319 | ENSBTAP00000008891 | EH domain binding protein 1. | EH domain binding protein 1 like 1. | 0.587 |
EHBP1 | MYO1A | ENSBTAP00000053319 | ENSBTAP00000068102 | EH domain binding protein 1. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.542 |
EHBP1 | PDLIM1 | ENSBTAP00000053319 | ENSBTAP00000014850 | EH domain binding protein 1. | PDZ and LIM domain protein 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity). | 0.639 |
EHBP1 | PDLIM2 | ENSBTAP00000053319 | ENSBTAP00000065726 | EH domain binding protein 1. | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity). | 0.639 |
EHBP1 | PDLIM5 | ENSBTAP00000053319 | ENSBTAP00000054445 | EH domain binding protein 1. | PDZ and LIM domain 5. | 0.708 |
EHBP1 | SMTNL1 | ENSBTAP00000053319 | ENSBTAP00000041378 | EH domain binding protein 1. | Smoothelin like 1. | 0.570 |
EHBP1 | SMTNL2 | ENSBTAP00000053319 | ENSBTAP00000027457 | EH domain binding protein 1. | Smoothelin-like protein 2; Belongs to the smoothelin family. | 0.570 |
EHBP1L1 | DPYSL3 | ENSBTAP00000008891 | ENSBTAP00000014091 | EH domain binding protein 1 like 1. | Dihydropyrimidinase like 3. | 0.569 |