node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJAP1 | KLHL21 | ENSBTAP00000061950 | ENSBTAP00000010998 | Adherens junctions associated protein 1. | Kelch-like protein 21; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome (By similarity). | 0.428 |
AJAP1 | THAP3 | ENSBTAP00000061950 | ENSBTAP00000014893 | Adherens junctions associated protein 1. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.502 |
BRAT1 | THAP3 | ENSBTAP00000019280 | ENSBTAP00000014893 | BRCA1 associated ATM activator 1. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.571 |
DNAJC11 | THAP3 | ENSBTAP00000014899 | ENSBTAP00000014893 | DnaJ homolog subfamily C member 11; Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.604 |
KLHL21 | AJAP1 | ENSBTAP00000010998 | ENSBTAP00000061950 | Kelch-like protein 21; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome (By similarity). | Adherens junctions associated protein 1. | 0.428 |
KLHL21 | THAP3 | ENSBTAP00000010998 | ENSBTAP00000014893 | Kelch-like protein 21; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome (By similarity). | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.560 |
NPHP4 | THAP3 | ENSBTAP00000042828 | ENSBTAP00000014893 | Nephrocystin 4. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.484 |
OGT | THAP3 | ENSBTAP00000042834 | ENSBTAP00000014893 | TPR_REGION domain-containing protein. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.583 |
SPSB3 | THAP3 | ENSBTAP00000022024 | ENSBTAP00000014893 | SPRY domain-containing SOCS box protein 3; May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the SPSB family. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.483 |
SULT2B1 | THAP3 | ENSBTAP00000055826 | ENSBTAP00000014893 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | 0.482 |
THAP3 | AJAP1 | ENSBTAP00000014893 | ENSBTAP00000061950 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | Adherens junctions associated protein 1. | 0.502 |
THAP3 | BRAT1 | ENSBTAP00000014893 | ENSBTAP00000019280 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | BRCA1 associated ATM activator 1. | 0.571 |
THAP3 | DNAJC11 | ENSBTAP00000014893 | ENSBTAP00000014899 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | DnaJ homolog subfamily C member 11; Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex. | 0.604 |
THAP3 | KLHL21 | ENSBTAP00000014893 | ENSBTAP00000010998 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | Kelch-like protein 21; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome (By similarity). | 0.560 |
THAP3 | NPHP4 | ENSBTAP00000014893 | ENSBTAP00000042828 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | Nephrocystin 4. | 0.484 |
THAP3 | OGT | ENSBTAP00000014893 | ENSBTAP00000042834 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | TPR_REGION domain-containing protein. | 0.583 |
THAP3 | SPSB3 | ENSBTAP00000014893 | ENSBTAP00000022024 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | SPRY domain-containing SOCS box protein 3; May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the SPSB family. | 0.483 |
THAP3 | SULT2B1 | ENSBTAP00000014893 | ENSBTAP00000055826 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.482 |
THAP3 | THAP4 | ENSBTAP00000014893 | ENSBTAP00000017628 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | THAP domain-containing protein 4. | 0.571 |
THAP3 | THAP6 | ENSBTAP00000014893 | ENSBTAP00000071027 | THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. | THAP domain containing 6. | 0.690 |