node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAMTS3 | ANGPTL8 | ENSBTAP00000053777 | ENSBTAP00000043232 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | Angiopoietin like 8. | 0.432 |
ADAMTS3 | HINT2 | ENSBTAP00000053777 | ENSBTAP00000015208 | ADAM metallopeptidase with thrombospondin type 1 motif 3. | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | 0.611 |
ANGPTL8 | ADAMTS3 | ENSBTAP00000043232 | ENSBTAP00000053777 | Angiopoietin like 8. | ADAM metallopeptidase with thrombospondin type 1 motif 3. | 0.432 |
ANGPTL8 | HINT2 | ENSBTAP00000043232 | ENSBTAP00000015208 | Angiopoietin like 8. | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | 0.664 |
ANGPTL8 | SPAG8 | ENSBTAP00000043232 | ENSBTAP00000015206 | Angiopoietin like 8. | Sperm associated antigen 8. | 0.627 |
ENDOG | FAHD2A | ENSBTAP00000016564 | ENSBTAP00000015354 | Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. | Fumarylacetoacetate hydrolase domain-containing protein 2; May have hydrolase activity. | 0.499 |
ENDOG | HINT2 | ENSBTAP00000016564 | ENSBTAP00000015208 | Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | 0.785 |
ENDOG | HSD17B10 | ENSBTAP00000016564 | ENSBTAP00000023642 | Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. | 3-hydroxyacyl-CoA dehydrogenase type-2; Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha- hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20- beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). Essential for structura [...] | 0.619 |
ENDOG | NDUFC2 | ENSBTAP00000016564 | ENSBTAP00000024209 | Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.464 |
FAHD2A | ENDOG | ENSBTAP00000015354 | ENSBTAP00000016564 | Fumarylacetoacetate hydrolase domain-containing protein 2; May have hydrolase activity. | Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. | 0.499 |
FAHD2A | HINT2 | ENSBTAP00000015354 | ENSBTAP00000015208 | Fumarylacetoacetate hydrolase domain-containing protein 2; May have hydrolase activity. | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | 0.898 |
HINT2 | ADAMTS3 | ENSBTAP00000015208 | ENSBTAP00000053777 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | ADAM metallopeptidase with thrombospondin type 1 motif 3. | 0.611 |
HINT2 | ANGPTL8 | ENSBTAP00000015208 | ENSBTAP00000043232 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | Angiopoietin like 8. | 0.664 |
HINT2 | ENDOG | ENSBTAP00000015208 | ENSBTAP00000016564 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | Endonuclease G, mitochondrial; Cleaves DNA at double-stranded (DG)n.(DC)n and at single- stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. | 0.785 |
HINT2 | FAHD2A | ENSBTAP00000015208 | ENSBTAP00000015354 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | Fumarylacetoacetate hydrolase domain-containing protein 2; May have hydrolase activity. | 0.898 |
HINT2 | HSD17B10 | ENSBTAP00000015208 | ENSBTAP00000023642 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | 3-hydroxyacyl-CoA dehydrogenase type-2; Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha- hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20- beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). Essential for structura [...] | 0.662 |
HINT2 | LSM7 | ENSBTAP00000015208 | ENSBTAP00000005939 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. | 0.770 |
HINT2 | NDUFA2 | ENSBTAP00000015208 | ENSBTAP00000020018 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.631 |
HINT2 | NDUFA7 | ENSBTAP00000015208 | ENSBTAP00000069350 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.700 |
HINT2 | NDUFC2 | ENSBTAP00000015208 | ENSBTAP00000024209 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity); Belongs to the HINT family. | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.722 |