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XDH protein (Bos taurus) - STRING interaction network
"XDH" - Xanthine dehydrogenase/oxidase in Bos taurus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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XDHXanthine dehydrogenase/oxidase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species (1332 aa)    
Predicted Functional Partners:
BTN1A1
Butyrophilin subfamily 1 member A1; May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity) (332 aa)
     
  0.975
UOX
Uricase; Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (304 aa)
   
 
  0.969
GDA
Bos taurus guanine deaminase (GDA), mRNA (454 aa)
 
 
  0.952
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (289 aa)
     
 
  0.936
TPMT
Thiopurine S-methyltransferase; Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family (245 aa)
         
  0.917
HPRT1
Hypoxanthine phosphoribosyltransferase 1; Belongs to the purine/pyrimidine phosphoribosyltransferase family (218 aa)
     
 
  0.914
ENSBTAG00000014685
Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5- phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity) (218 aa)
     
 
  0.913
CYP1A2
Cytochrome P450; Cytochromes P450 are a group of heme-thiolate monooxygenases (516 aa)
     
 
  0.905
NAT1
Arylamine N-acetyltransferase 1; Participates in the detoxification of a plethora of hydrazine and arylamine drugs (290 aa)
     
 
    0.904
XYLB
Xylulose kinase; Phosphorylates D-xylulose to produce D-xylulose 5- phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis (490 aa)
     
   
  0.869
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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