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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOGA14-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline; Belongs to the DapA family. (429 aa)    
Predicted Functional Partners:
CCDC127
Coiled-coil domain containing 127.
      
 0.785
HAGHL
Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
   
  
 0.747
ERICH3
Uncharacterized protein.
      
 0.742
CFAP61
Cilia and flagella associated protein 61.
      
 0.718
GLYATL3
Glycine-N-acyltransferase like 3.
   
  
 0.709
FAM174A
Family with sequence similarity 174 member A.
      
 0.701
TTC17
Tetratricopeptide repeat domain 17.
      
 0.687
WSB2
WD repeat and SOCS box-containing protein 2.
      
 0.682
SMIM3
Small integral membrane protein 3.
      
 0.682
GRHPR
Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.682
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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