node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSKMT | DNAJB11 | ENSBTAP00000059486 | ENSBTAP00000004094 | Citrate synthase lysine methyltransferase. | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | 0.415 |
CSKMT | SDF2 | ENSBTAP00000059486 | ENSBTAP00000073145 | Citrate synthase lysine methyltransferase. | Stromal cell-derived factor 2. | 0.598 |
DNAJB11 | CSKMT | ENSBTAP00000004094 | ENSBTAP00000059486 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | Citrate synthase lysine methyltransferase. | 0.415 |
DNAJB11 | HSP90B1 | ENSBTAP00000004094 | ENSBTAP00000004364 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. | 0.992 |
DNAJB11 | SDF2 | ENSBTAP00000004094 | ENSBTAP00000073145 | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | Stromal cell-derived factor 2. | 0.904 |
HSP90B1 | DNAJB11 | ENSBTAP00000004364 | ENSBTAP00000004094 | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | 0.992 |
HSP90B1 | SDF2 | ENSBTAP00000004364 | ENSBTAP00000073145 | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. | Stromal cell-derived factor 2. | 0.569 |
MOGS | SDF2 | ENSBTAP00000002408 | ENSBTAP00000073145 | Mannosyl-oligosaccharide glucosidase. | Stromal cell-derived factor 2. | 0.617 |
MOGS | THUMPD2 | ENSBTAP00000002408 | ENSBTAP00000006195 | Mannosyl-oligosaccharide glucosidase. | THUMP domain containing 2. | 0.607 |
MOGS | ZBTB37 | ENSBTAP00000002408 | ENSBTAP00000062829 | Mannosyl-oligosaccharide glucosidase. | Zinc finger and BTB domain containing 37. | 0.632 |
SDF2 | CSKMT | ENSBTAP00000073145 | ENSBTAP00000059486 | Stromal cell-derived factor 2. | Citrate synthase lysine methyltransferase. | 0.598 |
SDF2 | DNAJB11 | ENSBTAP00000073145 | ENSBTAP00000004094 | Stromal cell-derived factor 2. | DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. | 0.904 |
SDF2 | HSP90B1 | ENSBTAP00000073145 | ENSBTAP00000004364 | Stromal cell-derived factor 2. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. | 0.569 |
SDF2 | MOGS | ENSBTAP00000073145 | ENSBTAP00000002408 | Stromal cell-derived factor 2. | Mannosyl-oligosaccharide glucosidase. | 0.617 |
SDF2 | SEZ6 | ENSBTAP00000073145 | ENSBTAP00000069816 | Stromal cell-derived factor 2. | Seizure protein 6 homolog; May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity (By similarity). Belongs to the SEZ6 family. | 0.548 |
SDF2 | SLC25A35 | ENSBTAP00000073145 | ENSBTAP00000025036 | Stromal cell-derived factor 2. | Solute carrier family 25 member 35. | 0.686 |
SDF2 | SPAG1 | ENSBTAP00000073145 | ENSBTAP00000043499 | Stromal cell-derived factor 2. | Sperm associated antigen 1. | 0.536 |
SDF2 | THUMPD2 | ENSBTAP00000073145 | ENSBTAP00000006195 | Stromal cell-derived factor 2. | THUMP domain containing 2. | 0.572 |
SDF2 | TMTC3 | ENSBTAP00000073145 | ENSBTAP00000011881 | Stromal cell-derived factor 2. | Transmembrane O-mannosyltransferase targeting cadherins 3. | 0.566 |
SDF2 | ZBTB37 | ENSBTAP00000073145 | ENSBTAP00000062829 | Stromal cell-derived factor 2. | Zinc finger and BTB domain containing 37. | 0.606 |