Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIFM1 | BAK1 | ENSBTAP00000008987 | ENSBTAP00000000549 | Apoptosis inducing factor mitochondria associated 1. | Bcl-2 homologous antagonist/killer transcript variant 1. | 0.400 |
| AIFM1 | BAX | ENSBTAP00000008987 | ENSBTAP00000073472 | Apoptosis inducing factor mitochondria associated 1. | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | 0.920 |
| AIFM1 | BCL2 | ENSBTAP00000008987 | ENSBTAP00000025701 | Apoptosis inducing factor mitochondria associated 1. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.408 |
| AIFM1 | BCL2L11 | ENSBTAP00000008987 | ENSBTAP00000072134 | Apoptosis inducing factor mitochondria associated 1. | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. | 0.425 |
| AIFM1 | CYCS | ENSBTAP00000008987 | ENSBTAP00000007918 | Apoptosis inducing factor mitochondria associated 1. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.586 |
| AIFM1 | CYCT | ENSBTAP00000008987 | ENSBTAP00000031831 | Apoptosis inducing factor mitochondria associated 1. | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.476 |
| BAK1 | AIFM1 | ENSBTAP00000000549 | ENSBTAP00000008987 | Bcl-2 homologous antagonist/killer transcript variant 1. | Apoptosis inducing factor mitochondria associated 1. | 0.400 |
| BAK1 | BAX | ENSBTAP00000000549 | ENSBTAP00000073472 | Bcl-2 homologous antagonist/killer transcript variant 1. | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | 0.944 |
| BAK1 | BCL2 | ENSBTAP00000000549 | ENSBTAP00000025701 | Bcl-2 homologous antagonist/killer transcript variant 1. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.993 |
| BAK1 | BCL2L1 | ENSBTAP00000000549 | ENSBTAP00000070613 | Bcl-2 homologous antagonist/killer transcript variant 1. | BCL2-like 1 transcript variant 1. | 0.983 |
| BAK1 | BCL2L11 | ENSBTAP00000000549 | ENSBTAP00000072134 | Bcl-2 homologous antagonist/killer transcript variant 1. | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. | 0.959 |
| BAK1 | BID | ENSBTAP00000000549 | ENSBTAP00000040367 | Bcl-2 homologous antagonist/killer transcript variant 1. | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | 0.995 |
| BAK1 | CYCS | ENSBTAP00000000549 | ENSBTAP00000007918 | Bcl-2 homologous antagonist/killer transcript variant 1. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.972 |
| BAK1 | CYCT | ENSBTAP00000000549 | ENSBTAP00000031831 | Bcl-2 homologous antagonist/killer transcript variant 1. | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.970 |
| BAK1 | TP53 | ENSBTAP00000000549 | ENSBTAP00000001420 | Bcl-2 homologous antagonist/killer transcript variant 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.976 |
| BAX | AIFM1 | ENSBTAP00000073472 | ENSBTAP00000008987 | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | Apoptosis inducing factor mitochondria associated 1. | 0.920 |
| BAX | BAK1 | ENSBTAP00000073472 | ENSBTAP00000000549 | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | Bcl-2 homologous antagonist/killer transcript variant 1. | 0.944 |
| BAX | BCL2 | ENSBTAP00000073472 | ENSBTAP00000025701 | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.984 |
| BAX | BCL2L1 | ENSBTAP00000073472 | ENSBTAP00000070613 | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | BCL2-like 1 transcript variant 1. | 0.961 |
| BAX | BCL2L11 | ENSBTAP00000073472 | ENSBTAP00000072134 | Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. | 0.966 |
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