node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | BPGM | ENSBTAP00000057869 | ENSBTAP00000011713 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | 0.933 |
ALDOA | ENO1 | ENSBTAP00000057869 | ENSBTAP00000017839 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.979 |
ALDOA | GPI | ENSBTAP00000057869 | ENSBTAP00000073190 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.985 |
ALDOA | PGAM1 | ENSBTAP00000057869 | ENSBTAP00000032864 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate mutase 1; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. | 0.967 |
ALDOA | PGAM2 | ENSBTAP00000057869 | ENSBTAP00000019336 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate mutase 2; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.942 |
ALDOA | PGK1 | ENSBTAP00000057869 | ENSBTAP00000001187 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.929 |
ALDOA | PKLR | ENSBTAP00000057869 | ENSBTAP00000061000 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.940 |
ALDOA | PKM | ENSBTAP00000057869 | ENSBTAP00000044619 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.983 |
ALDOA | TPI1 | ENSBTAP00000057869 | ENSBTAP00000026358 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.996 |
BPGM | ALDOA | ENSBTAP00000011713 | ENSBTAP00000057869 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.933 |
BPGM | ENO1 | ENSBTAP00000011713 | ENSBTAP00000017839 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.978 |
BPGM | GPI | ENSBTAP00000011713 | ENSBTAP00000073190 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.933 |
BPGM | PGAM1 | ENSBTAP00000011713 | ENSBTAP00000032864 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Phosphoglycerate mutase 1; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. | 0.925 |
BPGM | PGAM2 | ENSBTAP00000011713 | ENSBTAP00000019336 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Phosphoglycerate mutase 2; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.933 |
BPGM | PGK1 | ENSBTAP00000011713 | ENSBTAP00000001187 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.988 |
BPGM | PKLR | ENSBTAP00000011713 | ENSBTAP00000061000 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.789 |
BPGM | PKM | ENSBTAP00000011713 | ENSBTAP00000044619 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.769 |
BPGM | TPI1 | ENSBTAP00000011713 | ENSBTAP00000026358 | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.931 |
ENO1 | ALDOA | ENSBTAP00000017839 | ENSBTAP00000057869 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.979 |
ENO1 | BPGM | ENSBTAP00000017839 | ENSBTAP00000011713 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | Bisphosphoglycerate mutase; Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3- bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. | 0.978 |