node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGRN | BCAN | ENSBTAP00000060572 | ENSBTAP00000065021 | Agrin. | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | 0.777 |
AGRN | BGN | ENSBTAP00000060572 | ENSBTAP00000044462 | Agrin. | Biglycan; May be involved in collagen fiber assembly. | 0.874 |
AGRN | FGF2 | ENSBTAP00000060572 | ENSBTAP00000007477 | Agrin. | Kidney-derived growth factor; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | 0.538 |
AGRN | GPC1 | ENSBTAP00000060572 | ENSBTAP00000060932 | Agrin. | Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting [...] | 0.773 |
AGRN | SDC1 | ENSBTAP00000060572 | ENSBTAP00000072853 | Agrin. | Syndecan-1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. | 0.726 |
AGRN | SDC2 | ENSBTAP00000060572 | ENSBTAP00000071799 | Agrin. | Syndecan-2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity). | 0.656 |
AGRN | SDC3 | ENSBTAP00000060572 | ENSBTAP00000065590 | Agrin. | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. | 0.731 |
AGRN | SDC4 | ENSBTAP00000060572 | ENSBTAP00000020125 | Agrin. | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. | 0.687 |
BCAN | AGRN | ENSBTAP00000065021 | ENSBTAP00000060572 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Agrin. | 0.777 |
BCAN | BGN | ENSBTAP00000065021 | ENSBTAP00000044462 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Biglycan; May be involved in collagen fiber assembly. | 0.793 |
BCAN | GPC1 | ENSBTAP00000065021 | ENSBTAP00000060932 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting [...] | 0.773 |
BCAN | SDC1 | ENSBTAP00000065021 | ENSBTAP00000072853 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Syndecan-1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. | 0.667 |
BCAN | SDC2 | ENSBTAP00000065021 | ENSBTAP00000071799 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Syndecan-2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity). | 0.513 |
BCAN | SDC3 | ENSBTAP00000065021 | ENSBTAP00000065590 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. | 0.636 |
BCAN | SDC4 | ENSBTAP00000065021 | ENSBTAP00000020125 | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. | 0.605 |
BGN | AGRN | ENSBTAP00000044462 | ENSBTAP00000060572 | Biglycan; May be involved in collagen fiber assembly. | Agrin. | 0.874 |
BGN | BCAN | ENSBTAP00000044462 | ENSBTAP00000065021 | Biglycan; May be involved in collagen fiber assembly. | Brevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. | 0.793 |
BGN | FGF2 | ENSBTAP00000044462 | ENSBTAP00000007477 | Biglycan; May be involved in collagen fiber assembly. | Kidney-derived growth factor; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | 0.588 |
BGN | GPC1 | ENSBTAP00000044462 | ENSBTAP00000060932 | Biglycan; May be involved in collagen fiber assembly. | Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting [...] | 0.773 |
BGN | SDC1 | ENSBTAP00000044462 | ENSBTAP00000072853 | Biglycan; May be involved in collagen fiber assembly. | Syndecan-1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. | 0.882 |