node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BOP1 | BRIX1 | ENSBTAP00000012938 | ENSBTAP00000056776 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.994 |
BOP1 | EBNA1BP2 | ENSBTAP00000012938 | ENSBTAP00000028708 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | EBNA1 binding protein 2. | 0.996 |
BOP1 | NIFK | ENSBTAP00000012938 | ENSBTAP00000031516 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.990 |
BOP1 | NOC2L | ENSBTAP00000012938 | ENSBTAP00000021980 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.999 |
BOP1 | NOP53 | ENSBTAP00000012938 | ENSBTAP00000040958 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | NOP53 ribosome biogenesis factor. | 0.708 |
BOP1 | PES1 | ENSBTAP00000012938 | ENSBTAP00000010163 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
BOP1 | RSL1D1 | ENSBTAP00000012938 | ENSBTAP00000019422 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage; Belongs to the universal ribosomal protein uL1 family. Highly divergent. | 0.994 |
BOP1 | UTP4 | ENSBTAP00000012938 | ENSBTAP00000008333 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | UTP4 small subunit processome component. | 0.889 |
BOP1 | WDR12 | ENSBTAP00000012938 | ENSBTAP00000020499 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.999 |
BOP1 | WDR3 | ENSBTAP00000012938 | ENSBTAP00000026561 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | WD repeat domain 3. | 0.967 |
BRIX1 | BOP1 | ENSBTAP00000056776 | ENSBTAP00000012938 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.994 |
BRIX1 | EBNA1BP2 | ENSBTAP00000056776 | ENSBTAP00000028708 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | EBNA1 binding protein 2. | 0.997 |
BRIX1 | NIFK | ENSBTAP00000056776 | ENSBTAP00000031516 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.999 |
BRIX1 | NOC2L | ENSBTAP00000056776 | ENSBTAP00000021980 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.993 |
BRIX1 | NOP53 | ENSBTAP00000056776 | ENSBTAP00000040958 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | NOP53 ribosome biogenesis factor. | 0.779 |
BRIX1 | PES1 | ENSBTAP00000056776 | ENSBTAP00000010163 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.986 |
BRIX1 | RSL1D1 | ENSBTAP00000056776 | ENSBTAP00000019422 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage; Belongs to the universal ribosomal protein uL1 family. Highly divergent. | 0.990 |
BRIX1 | UTP4 | ENSBTAP00000056776 | ENSBTAP00000008333 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | UTP4 small subunit processome component. | 0.872 |
BRIX1 | WDR12 | ENSBTAP00000056776 | ENSBTAP00000020499 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.989 |
BRIX1 | WDR3 | ENSBTAP00000056776 | ENSBTAP00000026561 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | WD repeat domain 3. | 0.834 |