node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTG1 | ESPN | ENSBTAP00000008132 | ENSBTAP00000057626 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Espin. | 0.415 |
ACTG1 | MYO1A | ENSBTAP00000008132 | ENSBTAP00000068102 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.574 |
ACTG1 | PDLIM1 | ENSBTAP00000008132 | ENSBTAP00000014850 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | PDZ and LIM domain protein 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity). | 0.545 |
ACTG1 | PDLIM4 | ENSBTAP00000008132 | ENSBTAP00000020501 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | PDZ and LIM domain protein 4; Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle. Involved in reorganization of the actin cytoskeleton (By similarity). In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transpo [...] | 0.442 |
ACTG1 | PDLIM5 | ENSBTAP00000008132 | ENSBTAP00000054445 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | PDZ and LIM domain 5. | 0.459 |
CALML5 | MYO1A | ENSBTAP00000018403 | ENSBTAP00000068102 | Calmodulin like 5. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.579 |
DPYSL3 | MYO1A | ENSBTAP00000014091 | ENSBTAP00000068102 | Dihydropyrimidinase like 3. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.720 |
DPYSL3 | PDLIM1 | ENSBTAP00000014091 | ENSBTAP00000014850 | Dihydropyrimidinase like 3. | PDZ and LIM domain protein 1; Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity). | 0.593 |
DPYSL3 | PDLIM4 | ENSBTAP00000014091 | ENSBTAP00000020501 | Dihydropyrimidinase like 3. | PDZ and LIM domain protein 4; Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle. Involved in reorganization of the actin cytoskeleton (By similarity). In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transpo [...] | 0.646 |
DPYSL3 | PDLIM5 | ENSBTAP00000014091 | ENSBTAP00000054445 | Dihydropyrimidinase like 3. | PDZ and LIM domain 5. | 0.540 |
ENSBTAP00000067191 | ESPN | ENSBTAP00000067191 | ENSBTAP00000057626 | MyTH4 domain-containing protein. | Espin. | 0.761 |
ENSBTAP00000067191 | MYO1A | ENSBTAP00000067191 | ENSBTAP00000068102 | MyTH4 domain-containing protein. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.705 |
ESPN | ACTG1 | ENSBTAP00000057626 | ENSBTAP00000008132 | Espin. | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | 0.415 |
ESPN | ENSBTAP00000067191 | ENSBTAP00000057626 | ENSBTAP00000067191 | Espin. | MyTH4 domain-containing protein. | 0.761 |
ESPN | MYO1A | ENSBTAP00000057626 | ENSBTAP00000068102 | Espin. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.659 |
KCTD16 | MYO1A | ENSBTAP00000025305 | ENSBTAP00000068102 | Potassium channel tetramerization domain containing 16. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.661 |
LGALS4 | MYO1A | ENSBTAP00000021701 | ENSBTAP00000068102 | Galectin-4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions (By similarity). | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.614 |
MYO1A | ACTG1 | ENSBTAP00000068102 | ENSBTAP00000008132 | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | 0.574 |
MYO1A | CALML5 | ENSBTAP00000068102 | ENSBTAP00000018403 | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Calmodulin like 5. | 0.579 |
MYO1A | DPYSL3 | ENSBTAP00000068102 | ENSBTAP00000014091 | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Dihydropyrimidinase like 3. | 0.720 |