node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BSG | SLC16A1 | ENSBTAP00000039862 | ENSBTAP00000020102 | Basigin. | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | 0.943 |
BSG | SLC2A1 | ENSBTAP00000039862 | ENSBTAP00000040563 | Basigin. | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. | 0.857 |
EMB | SLC16A1 | ENSBTAP00000053825 | ENSBTAP00000020102 | Embigin. | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | 0.852 |
HK2 | LDHA | ENSBTAP00000053231 | ENSBTAP00000047729 | Hexokinase 2. | L-lactate dehydrogenase A chain. | 0.903 |
HK2 | LDHB | ENSBTAP00000053231 | ENSBTAP00000069027 | Hexokinase 2. | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | 0.723 |
HK2 | SLC16A1 | ENSBTAP00000053231 | ENSBTAP00000020102 | Hexokinase 2. | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | 0.659 |
HK2 | SLC2A1 | ENSBTAP00000053231 | ENSBTAP00000040563 | Hexokinase 2. | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. | 0.783 |
LDHA | HK2 | ENSBTAP00000047729 | ENSBTAP00000053231 | L-lactate dehydrogenase A chain. | Hexokinase 2. | 0.903 |
LDHA | LDHB | ENSBTAP00000047729 | ENSBTAP00000069027 | L-lactate dehydrogenase A chain. | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | 0.976 |
LDHA | SLC16A1 | ENSBTAP00000047729 | ENSBTAP00000020102 | L-lactate dehydrogenase A chain. | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | 0.704 |
LDHA | SLC2A1 | ENSBTAP00000047729 | ENSBTAP00000040563 | L-lactate dehydrogenase A chain. | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. | 0.827 |
LDHB | HK2 | ENSBTAP00000069027 | ENSBTAP00000053231 | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | Hexokinase 2. | 0.723 |
LDHB | LDHA | ENSBTAP00000069027 | ENSBTAP00000047729 | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | L-lactate dehydrogenase A chain. | 0.976 |
LDHB | SLC16A1 | ENSBTAP00000069027 | ENSBTAP00000020102 | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | 0.699 |
LDHB | SLC2A1 | ENSBTAP00000069027 | ENSBTAP00000040563 | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. | 0.602 |
SLC16A1 | BSG | ENSBTAP00000020102 | ENSBTAP00000039862 | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | Basigin. | 0.943 |
SLC16A1 | EMB | ENSBTAP00000020102 | ENSBTAP00000053825 | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | Embigin. | 0.852 |
SLC16A1 | HK2 | ENSBTAP00000020102 | ENSBTAP00000053231 | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | Hexokinase 2. | 0.659 |
SLC16A1 | LDHA | ENSBTAP00000020102 | ENSBTAP00000047729 | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | L-lactate dehydrogenase A chain. | 0.704 |
SLC16A1 | LDHB | ENSBTAP00000020102 | ENSBTAP00000069027 | Monocarboxylate transporter 1; Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to [...] | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. | 0.699 |