| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADIPOQ | CA3 | ENSBTAP00000065019 | ENSBTAP00000020243 | Adiponectin; Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis [...] | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.589 |
| CA1 | CA13 | ENSBTAP00000043090 | ENSBTAP00000001324 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | 0.520 |
| CA1 | CA2 | ENSBTAP00000043090 | ENSBTAP00000023581 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | 0.774 |
| CA1 | CA3 | ENSBTAP00000043090 | ENSBTAP00000020243 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.538 |
| CA1 | CA4 | ENSBTAP00000043090 | ENSBTAP00000063467 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). Belongs to the alpha-carbonic anhydrase family. | 0.514 |
| CA1 | CA7 | ENSBTAP00000043090 | ENSBTAP00000065525 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. | 0.522 |
| CA1 | CABIN1 | ENSBTAP00000043090 | ENSBTAP00000018360 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Calcineurin binding protein 1. | 0.458 |
| CA1 | RPF2 | ENSBTAP00000043090 | ENSBTAP00000073241 | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.579 |
| CA13 | CA1 | ENSBTAP00000001324 | ENSBTAP00000043090 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | 0.520 |
| CA13 | CA2 | ENSBTAP00000001324 | ENSBTAP00000023581 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | 0.622 |
| CA13 | CA3 | ENSBTAP00000001324 | ENSBTAP00000020243 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.529 |
| CA13 | CA4 | ENSBTAP00000001324 | ENSBTAP00000063467 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). Belongs to the alpha-carbonic anhydrase family. | 0.512 |
| CA13 | CA7 | ENSBTAP00000001324 | ENSBTAP00000065525 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. | 0.535 |
| CA13 | CABIN1 | ENSBTAP00000001324 | ENSBTAP00000018360 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Calcineurin binding protein 1. | 0.458 |
| CA13 | RPF2 | ENSBTAP00000001324 | ENSBTAP00000073241 | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.579 |
| CA2 | CA1 | ENSBTAP00000023581 | ENSBTAP00000043090 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | Carbonic anhydrase 1; Reversible hydration of carbon dioxide. | 0.774 |
| CA2 | CA13 | ENSBTAP00000023581 | ENSBTAP00000001324 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. | 0.622 |
| CA2 | CA3 | ENSBTAP00000023581 | ENSBTAP00000020243 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | Carbonic anhydrase 3; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.548 |
| CA2 | CA4 | ENSBTAP00000023581 | ENSBTAP00000063467 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). Belongs to the alpha-carbonic anhydrase family. | 0.518 |
| CA2 | CA7 | ENSBTAP00000023581 | ENSBTAP00000065525 | Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. | Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. | 0.527 |
