node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B3GNT2 | B3GNT4 | ENSBTAP00000045821 | ENSBTAP00000005494 | Hexosyltransferase. | Hexosyltransferase. | 0.907 |
B3GNT2 | B4GALT1 | ENSBTAP00000045821 | ENSBTAP00000020286 | Hexosyltransferase. | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | 0.970 |
B3GNT2 | FUT6 | ENSBTAP00000045821 | ENSBTAP00000000529 | Hexosyltransferase. | Galactoside 3(4)-L-fucosyltransferase; May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of sialyl Lewis X and Lewis X/SSEA-1 antigens. It may be involved in blood group Lewis determination. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L- fucosyl links. | 0.933 |
B3GNT2 | FUT8 | ENSBTAP00000045821 | ENSBTAP00000026406 | Hexosyltransferase. | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. | 0.615 |
B3GNT2 | FUT9 | ENSBTAP00000045821 | ENSBTAP00000010501 | Hexosyltransferase. | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9; Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosynthesis in neurons which allows cell differentiation, cell adhesion, and initiation of neurite outgrowth. Also fucosylates di-, tri- and tetraantennary N-glycans linked to glycoproteins and the inner lacto [...] | 0.925 |
B3GNT2 | GGTA1 | ENSBTAP00000045821 | ENSBTAP00000065603 | Hexosyltransferase. | N-acetyllactosaminide alpha-1,3-galactosyltransferase; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3). Belongs to the glycosyltransferase 6 family. | 0.903 |
B3GNT2 | ST3GAL3 | ENSBTAP00000045821 | ENSBTAP00000060947 | Hexosyltransferase. | ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. | 0.597 |
B3GNT2 | ST3GAL6 | ENSBTAP00000045821 | ENSBTAP00000005868 | Hexosyltransferase. | Type 2 lactosamine alpha-2,3-sialyltransferase; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity). Belongs to the glycosyltransferase 29 family. | 0.957 |
B3GNT2 | ST6GAL1 | ENSBTAP00000045821 | ENSBTAP00000063809 | Hexosyltransferase. | ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. | 0.655 |
B3GNT4 | B3GNT2 | ENSBTAP00000005494 | ENSBTAP00000045821 | Hexosyltransferase. | Hexosyltransferase. | 0.907 |
B3GNT4 | B4GALT1 | ENSBTAP00000005494 | ENSBTAP00000020286 | Hexosyltransferase. | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | 0.959 |
B3GNT4 | FUT6 | ENSBTAP00000005494 | ENSBTAP00000000529 | Hexosyltransferase. | Galactoside 3(4)-L-fucosyltransferase; May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of sialyl Lewis X and Lewis X/SSEA-1 antigens. It may be involved in blood group Lewis determination. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L- fucosyl links. | 0.915 |
B3GNT4 | FUT8 | ENSBTAP00000005494 | ENSBTAP00000026406 | Hexosyltransferase. | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. | 0.511 |
B3GNT4 | FUT9 | ENSBTAP00000005494 | ENSBTAP00000010501 | Hexosyltransferase. | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9; Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosynthesis in neurons which allows cell differentiation, cell adhesion, and initiation of neurite outgrowth. Also fucosylates di-, tri- and tetraantennary N-glycans linked to glycoproteins and the inner lacto [...] | 0.938 |
B3GNT4 | GGTA1 | ENSBTAP00000005494 | ENSBTAP00000065603 | Hexosyltransferase. | N-acetyllactosaminide alpha-1,3-galactosyltransferase; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3). Belongs to the glycosyltransferase 6 family. | 0.901 |
B3GNT4 | ST3GAL3 | ENSBTAP00000005494 | ENSBTAP00000060947 | Hexosyltransferase. | ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. | 0.410 |
B3GNT4 | ST3GAL6 | ENSBTAP00000005494 | ENSBTAP00000005868 | Hexosyltransferase. | Type 2 lactosamine alpha-2,3-sialyltransferase; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity). Belongs to the glycosyltransferase 29 family. | 0.909 |
B3GNT4 | ST6GAL1 | ENSBTAP00000005494 | ENSBTAP00000063809 | Hexosyltransferase. | ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. | 0.509 |
B4GALT1 | B3GNT2 | ENSBTAP00000020286 | ENSBTAP00000045821 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Hexosyltransferase. | 0.970 |
B4GALT1 | B3GNT4 | ENSBTAP00000020286 | ENSBTAP00000005494 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Hexosyltransferase. | 0.959 |