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TPP1 protein (Bos taurus) - STRING interaction network
"TPP1" - Tripeptidyl-peptidase 1 precursor in Bos taurus
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TPP1Tripeptidyl-peptidase 1 precursor ; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity) (563 aa)    
Predicted Functional Partners:
PPT1
Palmitoyl-protein thioesterase 1 precursor ; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons (306 aa)
     
   
  0.813
CLN6
Ceroid-lipofuscinosis neuronal protein 6 (311 aa)
     
   
  0.791
CLN5
Ceroid-lipofuscinosis neuronal protein 5 (358 aa)
     
   
  0.790
CLN3
Battenin (438 aa)
     
   
  0.784
CLN8
Protein CLN8 (200 aa)
           
  0.733
MFSD8
Major facilitator superfamily domain-containing protein 8 (519 aa)
           
  0.663
DNAJC5
DnaJ homolog subfamily C member 5 ; May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (198 aa)
       
 
  0.618
DNAJC5B
DnaJ homolog subfamily C member 5B (199 aa)
       
 
  0.572
CTSD
Cathepsin D precursor ; Acid protease active in intracellular protein breakdown (412 aa)
     
   
  0.487
POT1
Uncharacterized protein (782 aa)
       
 
  0.469
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae, Bovidae sp. Adi Nefas, Bovinae, Pecora, Ruminantia, bovine, cattle, cow, domestic cattle, domestic cow, oxen, cattle
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