node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSBTAP00000057338 | SAR1A | ENSBTAP00000057338 | ENSBTAP00000022422 | Uncharacterized protein. | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | 0.838 |
ENSBTAP00000057338 | SAR1B | ENSBTAP00000057338 | ENSBTAP00000028280 | Uncharacterized protein. | GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). | 0.838 |
ENSBTAP00000057338 | SEC13 | ENSBTAP00000057338 | ENSBTAP00000023702 | Uncharacterized protein. | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum; Belongs to the WD repeat SEC13 family. | 0.921 |
ENSBTAP00000057338 | SEC23A | ENSBTAP00000057338 | ENSBTAP00000004831 | Uncharacterized protein. | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.875 |
ENSBTAP00000057338 | SEC23B | ENSBTAP00000057338 | ENSBTAP00000024348 | Uncharacterized protein. | Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. | 0.875 |
ENSBTAP00000057338 | SEC24A | ENSBTAP00000057338 | ENSBTAP00000040703 | Uncharacterized protein. | Protein transport protein Sec24A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may [...] | 0.892 |
ENSBTAP00000057338 | SEC24B | ENSBTAP00000057338 | ENSBTAP00000045766 | Uncharacterized protein. | SEC24 homolog B, COPII coat complex component. | 0.903 |
ENSBTAP00000057338 | SEC31A | ENSBTAP00000057338 | ENSBTAP00000027346 | Uncharacterized protein. | SEC31 homolog A, COPII coat complex component. | 0.540 |
ENSBTAP00000057338 | SEC31B | ENSBTAP00000057338 | ENSBTAP00000000099 | Uncharacterized protein. | SEC31 homolog B, COPII coat complex component. | 0.549 |
PREB | SAR1A | ENSBTAP00000009307 | ENSBTAP00000022422 | Prolactin regulatory element binding. | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | 0.978 |
PREB | SAR1B | ENSBTAP00000009307 | ENSBTAP00000028280 | Prolactin regulatory element binding. | GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). | 0.982 |
PREB | SEC13 | ENSBTAP00000009307 | ENSBTAP00000023702 | Prolactin regulatory element binding. | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum; Belongs to the WD repeat SEC13 family. | 0.471 |
PREB | SEC23A | ENSBTAP00000009307 | ENSBTAP00000004831 | Prolactin regulatory element binding. | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.724 |
PREB | SEC23B | ENSBTAP00000009307 | ENSBTAP00000024348 | Prolactin regulatory element binding. | Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. | 0.472 |
PREB | SEC24A | ENSBTAP00000009307 | ENSBTAP00000040703 | Prolactin regulatory element binding. | Protein transport protein Sec24A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may [...] | 0.665 |
PREB | SEC24B | ENSBTAP00000009307 | ENSBTAP00000045766 | Prolactin regulatory element binding. | SEC24 homolog B, COPII coat complex component. | 0.773 |
SAR1A | ENSBTAP00000057338 | ENSBTAP00000022422 | ENSBTAP00000057338 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | Uncharacterized protein. | 0.838 |
SAR1A | PREB | ENSBTAP00000022422 | ENSBTAP00000009307 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | Prolactin regulatory element binding. | 0.978 |
SAR1A | SAR1B | ENSBTAP00000022422 | ENSBTAP00000028280 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). | 0.909 |
SAR1A | SEC13 | ENSBTAP00000022422 | ENSBTAP00000023702 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum; Belongs to the WD repeat SEC13 family. | 0.983 |