Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCL2 | BCL2L1 | ENSBTAP00000025701 | ENSBTAP00000070613 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | BCL2-like 1 transcript variant 1. | 0.966 |
| BCL2 | BID | ENSBTAP00000025701 | ENSBTAP00000040367 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | 0.994 |
| BCL2 | CTSD | ENSBTAP00000025701 | ENSBTAP00000010022 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.948 |
| BCL2 | CTSL | ENSBTAP00000025701 | ENSBTAP00000036285 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | Cathepsin L1; Belongs to the peptidase C1 family. | 0.925 |
| BCL2 | CTSS | ENSBTAP00000025701 | ENSBTAP00000022774 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L; Belongs to the peptidase C1 family. | 0.950 |
| BCL2 | CTSV | ENSBTAP00000025701 | ENSBTAP00000022710 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. | 0.927 |
| BCL2L1 | BCL2 | ENSBTAP00000070613 | ENSBTAP00000025701 | BCL2-like 1 transcript variant 1. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.966 |
| BCL2L1 | BID | ENSBTAP00000070613 | ENSBTAP00000040367 | BCL2-like 1 transcript variant 1. | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | 0.983 |
| BCL2L1 | CTSD | ENSBTAP00000070613 | ENSBTAP00000010022 | BCL2-like 1 transcript variant 1. | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.909 |
| BCL2L1 | CTSL | ENSBTAP00000070613 | ENSBTAP00000036285 | BCL2-like 1 transcript variant 1. | Cathepsin L1; Belongs to the peptidase C1 family. | 0.900 |
| BCL2L1 | CTSS | ENSBTAP00000070613 | ENSBTAP00000022774 | BCL2-like 1 transcript variant 1. | Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L; Belongs to the peptidase C1 family. | 0.912 |
| BCL2L1 | CTSV | ENSBTAP00000070613 | ENSBTAP00000022710 | BCL2-like 1 transcript variant 1. | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. | 0.900 |
| BID | BCL2 | ENSBTAP00000040367 | ENSBTAP00000025701 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.994 |
| BID | BCL2L1 | ENSBTAP00000040367 | ENSBTAP00000070613 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | BCL2-like 1 transcript variant 1. | 0.983 |
| BID | CTSD | ENSBTAP00000040367 | ENSBTAP00000010022 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.920 |
| BID | CTSL | ENSBTAP00000040367 | ENSBTAP00000036285 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Cathepsin L1; Belongs to the peptidase C1 family. | 0.911 |
| BID | CTSS | ENSBTAP00000040367 | ENSBTAP00000022774 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L; Belongs to the peptidase C1 family. | 0.954 |
| BID | CTSV | ENSBTAP00000040367 | ENSBTAP00000022710 | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. | 0.911 |
| CD74 | CTSD | ENSBTAP00000067282 | ENSBTAP00000010022 | CD74 molecule. | Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. | 0.526 |
| CD74 | CTSL | ENSBTAP00000067282 | ENSBTAP00000036285 | CD74 molecule. | Cathepsin L1; Belongs to the peptidase C1 family. | 0.933 |
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