node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID4A | ARID4B | ENSBTAP00000025155 | ENSBTAP00000071668 | AT-rich interaction domain 4A. | AT-rich interaction domain 4B. | 0.907 |
ARID4A | BRMS1 | ENSBTAP00000025155 | ENSBTAP00000023526 | AT-rich interaction domain 4A. | Breast cancer metastasis-suppressor 1 homolog; Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity). | 0.974 |
ARID4A | HDAC1 | ENSBTAP00000025155 | ENSBTAP00000070647 | AT-rich interaction domain 4A. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.945 |
ARID4A | ING2 | ENSBTAP00000025155 | ENSBTAP00000054457 | AT-rich interaction domain 4A. | Inhibitor of growth protein. | 0.688 |
ARID4A | SAP18 | ENSBTAP00000025155 | ENSBTAP00000024791 | AT-rich interaction domain 4A. | Histone deacetylase complex subunit SAP18; Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or durin [...] | 0.698 |
ARID4A | SAP30 | ENSBTAP00000025155 | ENSBTAP00000020692 | AT-rich interaction domain 4A. | Sin3A associated protein 30. | 0.904 |
ARID4A | SAP30L | ENSBTAP00000025155 | ENSBTAP00000005222 | AT-rich interaction domain 4A. | SAP30 like. | 0.915 |
ARID4A | SIN3A | ENSBTAP00000025155 | ENSBTAP00000013167 | AT-rich interaction domain 4A. | SIN3 transcription regulator family member A. | 0.931 |
ARID4A | SIN3B | ENSBTAP00000025155 | ENSBTAP00000036272 | AT-rich interaction domain 4A. | SIN3 transcription regulator family member B. | 0.922 |
ARID4A | SINHCAF | ENSBTAP00000025155 | ENSBTAP00000001545 | AT-rich interaction domain 4A. | Family with sequence similarity 60, member A. | 0.794 |
ARID4B | ARID4A | ENSBTAP00000071668 | ENSBTAP00000025155 | AT-rich interaction domain 4B. | AT-rich interaction domain 4A. | 0.907 |
ARID4B | BRMS1 | ENSBTAP00000071668 | ENSBTAP00000023526 | AT-rich interaction domain 4B. | Breast cancer metastasis-suppressor 1 homolog; Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity). | 0.852 |
ARID4B | HDAC1 | ENSBTAP00000071668 | ENSBTAP00000070647 | AT-rich interaction domain 4B. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.941 |
ARID4B | ING2 | ENSBTAP00000071668 | ENSBTAP00000054457 | AT-rich interaction domain 4B. | Inhibitor of growth protein. | 0.713 |
ARID4B | SAP18 | ENSBTAP00000071668 | ENSBTAP00000024791 | AT-rich interaction domain 4B. | Histone deacetylase complex subunit SAP18; Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or durin [...] | 0.852 |
ARID4B | SAP30 | ENSBTAP00000071668 | ENSBTAP00000020692 | AT-rich interaction domain 4B. | Sin3A associated protein 30. | 0.947 |
ARID4B | SAP30L | ENSBTAP00000071668 | ENSBTAP00000005222 | AT-rich interaction domain 4B. | SAP30 like. | 0.852 |
ARID4B | SIN3A | ENSBTAP00000071668 | ENSBTAP00000013167 | AT-rich interaction domain 4B. | SIN3 transcription regulator family member A. | 0.968 |
ARID4B | SIN3B | ENSBTAP00000071668 | ENSBTAP00000036272 | AT-rich interaction domain 4B. | SIN3 transcription regulator family member B. | 0.864 |
ARID4B | SINHCAF | ENSBTAP00000071668 | ENSBTAP00000001545 | AT-rich interaction domain 4B. | Family with sequence similarity 60, member A. | 0.729 |