Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTNNB1 | IRS1 | ENSBTAP00000021838 | ENSBTAP00000028392 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion, as component of an [...] | Insulin receptor substrate 1. | 0.745 |
| CTNNB1 | PTPN1 | ENSBTAP00000021838 | ENSBTAP00000008678 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion, as component of an [...] | Tyrosine-protein phosphatase non-receptor type. | 0.925 |
| CTNNB1 | PTPN11 | ENSBTAP00000021838 | ENSBTAP00000002653 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion, as component of an [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.501 |
| CTNNB1 | PTPRF | ENSBTAP00000021838 | ENSBTAP00000065652 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion, as component of an [...] | Receptor-type tyrosine-protein phosphatase F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity). | 0.933 |
| INSR | IRS1 | ENSBTAP00000016858 | ENSBTAP00000028392 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 1. | 0.989 |
| INSR | IRS2 | ENSBTAP00000016858 | ENSBTAP00000049448 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 2. | 0.986 |
| INSR | IRS4 | ENSBTAP00000016858 | ENSBTAP00000008574 | Tyrosine-protein kinase receptor. | Insulin receptor substrate 4. | 0.966 |
| INSR | LOC107131843 | ENSBTAP00000016858 | ENSBTAP00000055405 | Tyrosine-protein kinase receptor. | Uncharacterized protein. | 0.970 |
| INSR | PTPN1 | ENSBTAP00000016858 | ENSBTAP00000008678 | Tyrosine-protein kinase receptor. | Tyrosine-protein phosphatase non-receptor type. | 0.995 |
| INSR | PTPN11 | ENSBTAP00000016858 | ENSBTAP00000002653 | Tyrosine-protein kinase receptor. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.955 |
| INSR | PTPRF | ENSBTAP00000016858 | ENSBTAP00000065652 | Tyrosine-protein kinase receptor. | Receptor-type tyrosine-protein phosphatase F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity). | 0.949 |
| IRS1 | CTNNB1 | ENSBTAP00000028392 | ENSBTAP00000021838 | Insulin receptor substrate 1. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion, as component of an [...] | 0.745 |
| IRS1 | INSR | ENSBTAP00000028392 | ENSBTAP00000016858 | Insulin receptor substrate 1. | Tyrosine-protein kinase receptor. | 0.989 |
| IRS1 | IRS2 | ENSBTAP00000028392 | ENSBTAP00000049448 | Insulin receptor substrate 1. | Insulin receptor substrate 2. | 0.948 |
| IRS1 | IRS4 | ENSBTAP00000028392 | ENSBTAP00000008574 | Insulin receptor substrate 1. | Insulin receptor substrate 4. | 0.792 |
| IRS1 | PTPN1 | ENSBTAP00000028392 | ENSBTAP00000008678 | Insulin receptor substrate 1. | Tyrosine-protein phosphatase non-receptor type. | 0.941 |
| IRS1 | PTPN11 | ENSBTAP00000028392 | ENSBTAP00000002653 | Insulin receptor substrate 1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.988 |
| IRS1 | PTPRF | ENSBTAP00000028392 | ENSBTAP00000065652 | Insulin receptor substrate 1. | Receptor-type tyrosine-protein phosphatase F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity). | 0.918 |
| IRS2 | INSR | ENSBTAP00000049448 | ENSBTAP00000016858 | Insulin receptor substrate 2. | Tyrosine-protein kinase receptor. | 0.986 |
| IRS2 | IRS1 | ENSBTAP00000049448 | ENSBTAP00000028392 | Insulin receptor substrate 2. | Insulin receptor substrate 1. | 0.948 |
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