node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALOX15 | PEBP1 | ENSBTAP00000015911 | ENSBTAP00000024107 | Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] | Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). Belongs to the phosphatidylethanolamine-binding protein family. | 0.855 |
ARAF | PEBP1 | ENSBTAP00000006653 | ENSBTAP00000024107 | Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. | Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). Belongs to the phosphatidylethanolamine-binding protein family. | 0.693 |
DAP3 | MRPL10 | ENSBTAP00000001589 | ENSBTAP00000002395 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 39S ribosomal protein L10, mitochondrial. | 0.975 |
DAP3 | MRPL12 | ENSBTAP00000001589 | ENSBTAP00000048266 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 0.944 |
DAP3 | MRPL13 | ENSBTAP00000001589 | ENSBTAP00000008903 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 0.979 |
DAP3 | MRPL16 | ENSBTAP00000001589 | ENSBTAP00000028236 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 39S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. | 0.973 |
DAP3 | MRPL4 | ENSBTAP00000001589 | ENSBTAP00000057411 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.978 |
DAP3 | MRPL40 | ENSBTAP00000001589 | ENSBTAP00000026501 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | Mitochondrial ribosomal protein L40. | 0.986 |
DAP3 | MRPL46 | ENSBTAP00000001589 | ENSBTAP00000026420 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 39S ribosomal protein L46, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family. | 0.977 |
DAP3 | PEBP1 | ENSBTAP00000001589 | ENSBTAP00000024107 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). Belongs to the phosphatidylethanolamine-binding protein family. | 0.700 |
MRPL10 | DAP3 | ENSBTAP00000002395 | ENSBTAP00000001589 | 39S ribosomal protein L10, mitochondrial. | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 0.975 |
MRPL10 | MRPL12 | ENSBTAP00000002395 | ENSBTAP00000048266 | 39S ribosomal protein L10, mitochondrial. | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 0.921 |
MRPL10 | MRPL13 | ENSBTAP00000002395 | ENSBTAP00000008903 | 39S ribosomal protein L10, mitochondrial. | 39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. | 0.983 |
MRPL10 | MRPL16 | ENSBTAP00000002395 | ENSBTAP00000028236 | 39S ribosomal protein L10, mitochondrial. | 39S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. | 0.986 |
MRPL10 | MRPL4 | ENSBTAP00000002395 | ENSBTAP00000057411 | 39S ribosomal protein L10, mitochondrial. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.976 |
MRPL10 | MRPL40 | ENSBTAP00000002395 | ENSBTAP00000026501 | 39S ribosomal protein L10, mitochondrial. | Mitochondrial ribosomal protein L40. | 0.959 |
MRPL10 | MRPL46 | ENSBTAP00000002395 | ENSBTAP00000026420 | 39S ribosomal protein L10, mitochondrial. | 39S ribosomal protein L46, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family. | 0.957 |
MRPL10 | PEBP1 | ENSBTAP00000002395 | ENSBTAP00000024107 | 39S ribosomal protein L10, mitochondrial. | Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). Belongs to the phosphatidylethanolamine-binding protein family. | 0.705 |
MRPL12 | DAP3 | ENSBTAP00000048266 | ENSBTAP00000001589 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. | 0.944 |
MRPL12 | MRPL10 | ENSBTAP00000048266 | ENSBTAP00000002395 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L10, mitochondrial. | 0.921 |