STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPRC5CG-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways (442 aa)    
Predicted Functional Partners:
OTOP3
Uncharacterized protein; Bos taurus otopetrin 3 (OTOP3), mRNA
      
 0.659
GPR135
G protein-coupled receptor 135
      
 0.635
GRM2
Glutamate receptor, metabotropic 2
      
 0.630
RNF157
Bos taurus ring finger protein 157 (RNF157), mRNA
      
 0.616
GPR176
G protein-coupled receptor 176
      
 0.558
SERINC2
Uncharacterized protein; Bos taurus serine incorporator 2 (SERINC2), mRNA
   
  
 0.550
GPR137B
Bos taurus G protein-coupled receptor 137B (GPR137B), mRNA
      
 0.539
CRTC1
Bos taurus CREB regulated transcription coactivator 1 (CRTC1), mRNA
      
 0.539
GPR174
G protein-coupled receptor 174
      
 0.537
GPR158
Probable G-protein coupled receptor 158; Orphan receptor
      
 0.537
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
Server load: low (15%) [HD]