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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPRC5CG-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling pathways. (443 aa)    
Predicted Functional Partners:
WDR5B
WD repeat domain 5B.
      
 0.680
CNTLN
Centlein.
      
 0.637
SAMD4B
Sterile alpha motif domain containing 4B.
      
 0.629
GPR107
G protein-coupled receptor 107.
      
 0.628
GPR180
G protein-coupled receptor 180.
      
 0.626
GPR158
Probable G-protein coupled receptor 158; Orphan receptor; Belongs to the G-protein coupled receptor 3 family.
      
 0.587
OTOP3
Otopetrin 3.
      
 0.570
GPR135
G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.
      
 0.569
ADGRG6
Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family.
      
 0.558
TAS1R3
Taste 1 receptor member 3.
      
 0.552
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.