STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC30A7Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity). (376 aa)    
Predicted Functional Partners:
SLC39A1
Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body (By similarity). Belongs to the ZIP transporter (TC 2.A.5) family.
   
 
 0.827
SLC39A11
Zinc transporter ZIP11; Functions as a cellular zinc transporter. Belongs to the ZIP transporter (TC 2.A.5) family.
   
 
 0.816
SLC39A13
Zinc transporter ZIP13; Acts as a zinc-influx transporter.
   
 
 0.811
SLC39A14
Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron.
  
 
 0.795
SLC30A8
Solute carrier family 30 member 8.
  
 
 
 0.787
SLC30A9
Solute carrier family 30 member 9.
  
 
 0.774
SLC39A9
Solute carrier family 39 member 9.
   
 
 0.747
SLC39A12
Zinc transporter ZIP12; Acts as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
  
 
 0.746
SLC39A7
Solute carrier family 39 (Zinc transporter), member 7.
  
 
 0.720
SLC39A2
Solute carrier family 39 member 2.
   
 
 0.688
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.