STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSBTAP00000025593Pregnancy-associated glycoprotein 1; Appears to be proteolytically inactive; Belongs to the peptidase A1 family (380 aa)    
Predicted Functional Partners:
DST
Dystonin isoform x1; Dystonin
   
 
 0.881
PRP1
Placental prolactin-related protein 1; Placental prolactin-related proteins may play a specific role during gestation
   
  
 0.765
IFN-TAU
Uncharacterized protein loc509166 precursor; IFN-tau; Bos taurus interferon-tau-like (IFN-TAU), mRNA
      
 0.589
MX2
Interferon-induced gtp-binding protein mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV)
   
 
 0.549
ISG15
Ubiquitin cross-reactive protein; Ubiquitin-like protein ISG15; Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein. Exhibits antiviral activity towards both DNA and RNA viruses. The secreted form of ISG15 can: induce natural killer cell proliferation, augment lymphok [...]
   
 
 0.546
RTP4
Receptor-transporting protein 4; Receptor (chemosensory) transporter protein 4
      
 0.518
APLP2
Amyloid beta (A4) precursor-like protein 2
    
 0.455
APP
Amyloid-beta a4 protein precursor; Amyloid-beta A4 protein; Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O)
    
 0.455
CSH2
Bos taurus chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA
   
  
 0.438
PLAC8
Placenta-specific gene 8 protein; Bos taurus placenta-specific 8 (PLAC8), mRNA
      
 0.410
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
Server load: low (6%) [HD]