node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHAD | ITGA2 | ENSBTAP00000028386 | ENSBTAP00000025685 | Chondroadherin minor form; Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. | Integrin alpha-2; Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. | 0.916 |
CHAD | ITGB1 | ENSBTAP00000028386 | ENSBTAP00000052015 | Chondroadherin minor form; Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.902 |
CHAD | ITGB3 | ENSBTAP00000028386 | ENSBTAP00000013173 | Chondroadherin minor form; Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. | Integrin beta; Belongs to the integrin beta chain family. | 0.694 |
CHAD | PTK2 | ENSBTAP00000028386 | ENSBTAP00000065036 | Chondroadherin minor form; Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.652 |
COL1A1 | COL1A2 | ENSBTAP00000017420 | ENSBTAP00000033771 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.999 |
COL1A1 | COL3A1 | ENSBTAP00000017420 | ENSBTAP00000028617 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen alpha-1(III) chain. | 0.999 |
COL1A1 | ITGA2 | ENSBTAP00000017420 | ENSBTAP00000025685 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Integrin alpha-2; Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. | 0.969 |
COL1A1 | ITGB1 | ENSBTAP00000017420 | ENSBTAP00000052015 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.971 |
COL1A1 | ITGB3 | ENSBTAP00000017420 | ENSBTAP00000013173 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Integrin beta; Belongs to the integrin beta chain family. | 0.890 |
COL1A1 | PTK2 | ENSBTAP00000017420 | ENSBTAP00000065036 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.681 |
COL1A2 | COL1A1 | ENSBTAP00000033771 | ENSBTAP00000017420 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | 0.999 |
COL1A2 | COL3A1 | ENSBTAP00000033771 | ENSBTAP00000028617 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen alpha-1(III) chain. | 0.999 |
COL1A2 | ITGA2 | ENSBTAP00000033771 | ENSBTAP00000025685 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Integrin alpha-2; Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. | 0.951 |
COL1A2 | ITGB1 | ENSBTAP00000033771 | ENSBTAP00000052015 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.973 |
COL1A2 | ITGB3 | ENSBTAP00000033771 | ENSBTAP00000013173 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Integrin beta; Belongs to the integrin beta chain family. | 0.857 |
COL1A2 | PTK2 | ENSBTAP00000033771 | ENSBTAP00000065036 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.663 |
COL3A1 | COL1A1 | ENSBTAP00000028617 | ENSBTAP00000017420 | Collagen alpha-1(III) chain. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | 0.999 |
COL3A1 | COL1A2 | ENSBTAP00000028617 | ENSBTAP00000033771 | Collagen alpha-1(III) chain. | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.999 |
COL3A1 | ITGA2 | ENSBTAP00000028617 | ENSBTAP00000025685 | Collagen alpha-1(III) chain. | Integrin alpha-2; Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. | 0.964 |
COL3A1 | ITGB1 | ENSBTAP00000028617 | ENSBTAP00000052015 | Collagen alpha-1(III) chain. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.948 |