node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCT7 | PPM1G | ENSBTAP00000016954 | ENSBTAP00000026003 | T-complex protein 1 subunit eta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin; Belongs to the TCP-1 chaperonin family. | Protein phosphatase 1G. | 0.624 |
CCT7 | PPP4C | ENSBTAP00000016954 | ENSBTAP00000017178 | T-complex protein 1 subunit eta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin; Belongs to the TCP-1 chaperonin family. | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | 0.641 |
PPIL4 | PPM1G | ENSBTAP00000022582 | ENSBTAP00000026003 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Protein phosphatase 1G. | 0.733 |
PPIL4 | TCEAL4 | ENSBTAP00000022582 | ENSBTAP00000011172 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Uncharacterized protein. | 0.686 |
PPIL4 | USP7 | ENSBTAP00000022582 | ENSBTAP00000007177 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.636 |
PPM1G | CCT7 | ENSBTAP00000026003 | ENSBTAP00000016954 | Protein phosphatase 1G. | T-complex protein 1 subunit eta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin; Belongs to the TCP-1 chaperonin family. | 0.624 |
PPM1G | PPIL4 | ENSBTAP00000026003 | ENSBTAP00000022582 | Protein phosphatase 1G. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | 0.733 |
PPM1G | PPM1H | ENSBTAP00000026003 | ENSBTAP00000015736 | Protein phosphatase 1G. | Protein phosphatase, Mg2+/Mn2+ dependent 1H. | 0.679 |
PPM1G | PPM1M | ENSBTAP00000026003 | ENSBTAP00000003860 | Protein phosphatase 1G. | Protein phosphatase, Mg2+/Mn2+ dependent 1M. | 0.589 |
PPM1G | PPP4C | ENSBTAP00000026003 | ENSBTAP00000017178 | Protein phosphatase 1G. | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | 0.646 |
PPM1G | SF3A2 | ENSBTAP00000026003 | ENSBTAP00000062091 | Protein phosphatase 1G. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | 0.591 |
PPM1G | SF3A3 | ENSBTAP00000026003 | ENSBTAP00000065151 | Protein phosphatase 1G. | Splicing factor 3a, subunit 3, 60kDa. | 0.629 |
PPM1G | TCEAL4 | ENSBTAP00000026003 | ENSBTAP00000011172 | Protein phosphatase 1G. | Uncharacterized protein. | 0.622 |
PPM1G | TRIM28 | ENSBTAP00000026003 | ENSBTAP00000008424 | Protein phosphatase 1G. | Tripartite motif containing 28. | 0.582 |
PPM1G | USP7 | ENSBTAP00000026003 | ENSBTAP00000007177 | Protein phosphatase 1G. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.752 |
PPM1H | PPM1G | ENSBTAP00000015736 | ENSBTAP00000026003 | Protein phosphatase, Mg2+/Mn2+ dependent 1H. | Protein phosphatase 1G. | 0.679 |
PPM1M | PPM1G | ENSBTAP00000003860 | ENSBTAP00000026003 | Protein phosphatase, Mg2+/Mn2+ dependent 1M. | Protein phosphatase 1G. | 0.589 |
PPP4C | CCT7 | ENSBTAP00000017178 | ENSBTAP00000016954 | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | T-complex protein 1 subunit eta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin; Belongs to the TCP-1 chaperonin family. | 0.641 |
PPP4C | PPM1G | ENSBTAP00000017178 | ENSBTAP00000026003 | Serine/threonine-protein phosphatase 4 catalytic subunit; Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2- PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphor [...] | Protein phosphatase 1G. | 0.646 |
SF3A2 | PPM1G | ENSBTAP00000062091 | ENSBTAP00000026003 | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | Protein phosphatase 1G. | 0.591 |