node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | ALDOC | ENSBTAP00000057869 | ENSBTAP00000017416 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.957 |
ALDOA | ENO1 | ENSBTAP00000057869 | ENSBTAP00000017839 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.979 |
ALDOA | ENSBTAP00000058833 | ENSBTAP00000057869 | ENSBTAP00000058833 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.708 |
ALDOA | GAPDH | ENSBTAP00000057869 | ENSBTAP00000062798 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.993 |
ALDOA | GAPDHS | ENSBTAP00000057869 | ENSBTAP00000021166 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.978 |
ALDOA | GPI | ENSBTAP00000057869 | ENSBTAP00000073190 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.985 |
ALDOA | PGK1 | ENSBTAP00000057869 | ENSBTAP00000001187 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.929 |
ALDOA | TALDO1 | ENSBTAP00000057869 | ENSBTAP00000013650 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.976 |
ALDOA | TKFC | ENSBTAP00000057869 | ENSBTAP00000069894 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | ATP-dependent dihydroxyacetone kinase; Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1- mediated cellular antiviral response. | 0.915 |
ALDOA | TPI1 | ENSBTAP00000057869 | ENSBTAP00000026358 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.996 |
ALDOC | ALDOA | ENSBTAP00000017416 | ENSBTAP00000057869 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.957 |
ALDOC | ENO1 | ENSBTAP00000017416 | ENSBTAP00000017839 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.962 |
ALDOC | ENSBTAP00000058833 | ENSBTAP00000017416 | ENSBTAP00000058833 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.644 |
ALDOC | GAPDH | ENSBTAP00000017416 | ENSBTAP00000062798 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.979 |
ALDOC | GAPDHS | ENSBTAP00000017416 | ENSBTAP00000021166 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.969 |
ALDOC | GPI | ENSBTAP00000017416 | ENSBTAP00000073190 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.961 |
ALDOC | PGK1 | ENSBTAP00000017416 | ENSBTAP00000001187 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.882 |
ALDOC | TALDO1 | ENSBTAP00000017416 | ENSBTAP00000013650 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.972 |
ALDOC | TKFC | ENSBTAP00000017416 | ENSBTAP00000069894 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | ATP-dependent dihydroxyacetone kinase; Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1- mediated cellular antiviral response. | 0.907 |
ALDOC | TPI1 | ENSBTAP00000017416 | ENSBTAP00000026358 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.991 |