node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD79A | ENSBTAP00000059753 | ENSBTAP00000002451 | ENSBTAP00000059753 | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | Uncharacterized protein. | 0.568 |
CD79A | JCHAIN | ENSBTAP00000002451 | ENSBTAP00000024666 | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | Joining chain of multimeric IgA and IgM. | 0.856 |
CD79A | LOC100300716 | ENSBTAP00000002451 | ENSBTAP00000055719 | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | Ig-like domain-containing protein. | 0.575 |
CD79A | LOC104968484 | ENSBTAP00000002451 | ENSBTAP00000069291 | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | Ig-like domain-containing protein. | 0.633 |
CD79A | PIGR | ENSBTAP00000002451 | ENSBTAP00000026377 | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.837 |
CSN3 | LTF | ENSBTAP00000028685 | ENSBTAP00000001704 | Casoplatelin; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. Casoplatelin inhibits platelet aggregation; Belongs to the kappa-casein family. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria. | 0.845 |
CSN3 | PIGR | ENSBTAP00000028685 | ENSBTAP00000026377 | Casoplatelin; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. Casoplatelin inhibits platelet aggregation; Belongs to the kappa-casein family. | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.757 |
ENSBTAP00000059753 | CD79A | ENSBTAP00000059753 | ENSBTAP00000002451 | Uncharacterized protein. | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | 0.568 |
ENSBTAP00000059753 | JCHAIN | ENSBTAP00000059753 | ENSBTAP00000024666 | Uncharacterized protein. | Joining chain of multimeric IgA and IgM. | 0.930 |
ENSBTAP00000059753 | LOC100300716 | ENSBTAP00000059753 | ENSBTAP00000055719 | Uncharacterized protein. | Ig-like domain-containing protein. | 0.914 |
ENSBTAP00000059753 | LOC104968484 | ENSBTAP00000059753 | ENSBTAP00000069291 | Uncharacterized protein. | Ig-like domain-containing protein. | 0.956 |
ENSBTAP00000059753 | PIGR | ENSBTAP00000059753 | ENSBTAP00000026377 | Uncharacterized protein. | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.909 |
IL2 | JCHAIN | ENSBTAP00000027819 | ENSBTAP00000024666 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Joining chain of multimeric IgA and IgM. | 0.780 |
IL2 | LTF | ENSBTAP00000027819 | ENSBTAP00000001704 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria. | 0.590 |
IL2 | PIGA | ENSBTAP00000027819 | ENSBTAP00000066131 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Phosphatidylinositol glycan anchor biosynthesis class A. | 0.434 |
IL2 | PIGR | ENSBTAP00000027819 | ENSBTAP00000026377 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. | 0.810 |
JCHAIN | CD79A | ENSBTAP00000024666 | ENSBTAP00000002451 | Joining chain of multimeric IgA and IgM. | B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...] | 0.856 |
JCHAIN | ENSBTAP00000059753 | ENSBTAP00000024666 | ENSBTAP00000059753 | Joining chain of multimeric IgA and IgM. | Uncharacterized protein. | 0.930 |
JCHAIN | IL2 | ENSBTAP00000024666 | ENSBTAP00000027819 | Joining chain of multimeric IgA and IgM. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.780 |
JCHAIN | LOC100300716 | ENSBTAP00000024666 | ENSBTAP00000055719 | Joining chain of multimeric IgA and IgM. | Ig-like domain-containing protein. | 0.718 |