node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BIRC2 | BIRC3 | ENSBTAP00000046955 | ENSBTAP00000034604 | Baculoviral IAP repeat containing 2. | Baculoviral IAP repeat-containing 3. | 0.912 |
BIRC2 | BIRC5 | ENSBTAP00000046955 | ENSBTAP00000018046 | Baculoviral IAP repeat containing 2. | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.942 |
BIRC2 | DIABLO | ENSBTAP00000046955 | ENSBTAP00000005496 | Baculoviral IAP repeat containing 2. | Diablo IAP-binding mitochondrial protein. | 0.970 |
BIRC2 | HTRA2 | ENSBTAP00000046955 | ENSBTAP00000026804 | Baculoviral IAP repeat containing 2. | Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis (By similarity). | 0.946 |
BIRC2 | TNFRSF1A | ENSBTAP00000046955 | ENSBTAP00000071830 | Baculoviral IAP repeat containing 2. | Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). | 0.978 |
BIRC2 | XIAP | ENSBTAP00000046955 | ENSBTAP00000058232 | Baculoviral IAP repeat containing 2. | RING-type domain-containing protein. | 0.950 |
BIRC3 | BIRC2 | ENSBTAP00000034604 | ENSBTAP00000046955 | Baculoviral IAP repeat-containing 3. | Baculoviral IAP repeat containing 2. | 0.912 |
BIRC3 | BIRC5 | ENSBTAP00000034604 | ENSBTAP00000018046 | Baculoviral IAP repeat-containing 3. | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | 0.936 |
BIRC3 | DIABLO | ENSBTAP00000034604 | ENSBTAP00000005496 | Baculoviral IAP repeat-containing 3. | Diablo IAP-binding mitochondrial protein. | 0.965 |
BIRC3 | HTRA2 | ENSBTAP00000034604 | ENSBTAP00000026804 | Baculoviral IAP repeat-containing 3. | Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis (By similarity). | 0.942 |
BIRC3 | TNFRSF1A | ENSBTAP00000034604 | ENSBTAP00000071830 | Baculoviral IAP repeat-containing 3. | Tumor necrosis factor receptor superfamily member 1A; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). | 0.978 |
BIRC3 | XIAP | ENSBTAP00000034604 | ENSBTAP00000058232 | Baculoviral IAP repeat-containing 3. | RING-type domain-containing protein. | 0.945 |
BIRC5 | BIRC2 | ENSBTAP00000018046 | ENSBTAP00000046955 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Baculoviral IAP repeat containing 2. | 0.942 |
BIRC5 | BIRC3 | ENSBTAP00000018046 | ENSBTAP00000034604 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Baculoviral IAP repeat-containing 3. | 0.936 |
BIRC5 | DIABLO | ENSBTAP00000018046 | ENSBTAP00000005496 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Diablo IAP-binding mitochondrial protein. | 0.986 |
BIRC5 | HTRA2 | ENSBTAP00000018046 | ENSBTAP00000026804 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis (By similarity). | 0.927 |
BIRC5 | XIAP | ENSBTAP00000018046 | ENSBTAP00000058232 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] | RING-type domain-containing protein. | 0.898 |
CYCS | CYCT | ENSBTAP00000007918 | ENSBTAP00000031831 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.916 |
CYCS | DIABLO | ENSBTAP00000007918 | ENSBTAP00000005496 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | Diablo IAP-binding mitochondrial protein. | 0.860 |
CYCS | HTRA2 | ENSBTAP00000007918 | ENSBTAP00000026804 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | Serine protease HTRA2, mitochondrial; Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase- independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis (By similarity). | 0.977 |